Literature DB >> 28696328

Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology.

David Masopust1, Christine P Sivula2, Stephen C Jameson3.   

Abstract

Mouse models have enabled breakthroughs in our understanding of the immune system, but it has become increasingly popular to emphasize their shortcomings when translating observations to humans. This review provides a brief summary of mouse natural history, husbandry, and the pros and cons of pursuing basic research in mice versus humans. Opportunities are discussed for extending the predictive translational value of mouse research, with an emphasis on exploitation of a "dirty" mouse model that better mimics the diverse infectious history that is typical of most humans.
Copyright © 2017 by The American Association of Immunologists, Inc.

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Mesh：

Year:  2017        PMID： 28696328      PMCID： PMC5512602          DOI： 10.4049/jimmunol.1700453

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  45 in total

1.  Variation in the human immune system is largely driven by non-heritable influences.

Authors:  Petter Brodin; Vladimir Jojic; Tianxiang Gao; Sanchita Bhattacharya; Cesar J Lopez Angel; David Furman; Shai Shen-Orr; Cornelia L Dekker; Gary E Swan; Atul J Butte; Holden T Maecker; Mark M Davis
Journal:  Cell       Date:  2015-01-15       Impact factor: 41.582

Review 2.  Mouse models of human disease. Part I: techniques and resources for genetic analysis in mice.

Authors:  M A Bedell; N A Jenkins; N G Copeland
Journal:  Genes Dev       Date:  1997-01-01       Impact factor: 11.361

3.  Genomic responses in mouse models greatly mimic human inflammatory diseases.

Authors:  Keizo Takao; Tsuyoshi Miyakawa
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-04       Impact factor: 11.205

Review 4.  The core gut microbiome, energy balance and obesity.

Authors:  Peter J Turnbaugh; Jeffrey I Gordon
Journal:  J Physiol       Date:  2009-06-02       Impact factor: 5.182

Review 5.  No one is naive: the significance of heterologous T-cell immunity.

Authors:  Raymond M Welsh; Liisa K Selin
Journal:  Nat Rev Immunol       Date:  2002-06       Impact factor: 53.106

6.  Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation.

Authors:  Jernej Godec; Yan Tan; Arthur Liberzon; Pablo Tamayo; Sanchita Bhattacharya; Atul J Butte; Jill P Mesirov; W Nicholas Haining
Journal:  Immunity       Date:  2016-01-12       Impact factor: 31.745

7.  Immune-cell lineage commitment: translation from mice to humans.

Authors:  Kimberly J Payne; Gay M Crooks
Journal:  Immunity       Date:  2007-06       Impact factor: 31.745

Review 8.  Accelerating next-generation vaccine development for global disease prevention.

Authors:  Wayne C Koff; Dennis R Burton; Philip R Johnson; Bruce D Walker; Charles R King; Gary J Nabel; Rafi Ahmed; Maharaj K Bhan; Stanley A Plotkin
Journal:  Science       Date:  2013-05-31       Impact factor: 47.728

9.  Innate immunity and intestinal microbiota in the development of Type 1 diabetes.

Authors:  Li Wen; Ruth E Ley; Pavel Yu Volchkov; Peter B Stranges; Lia Avanesyan; Austin C Stonebraker; Changyun Hu; F Susan Wong; Gregory L Szot; Jeffrey A Bluestone; Jeffrey I Gordon; Alexander V Chervonsky
Journal:  Nature       Date:  2008-09-21       Impact factor: 49.962

10.  A prescription for human immunology.

Authors:  Mark M Davis
Journal:  Immunity       Date:  2008-12-19       Impact factor: 31.745
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  78 in total

Review 1.  Emerging insights into human health and NK cell biology from the study of NK cell deficiencies.

Authors:  Emily M Mace; Jordan S Orange
Journal:  Immunol Rev       Date:  2019-01       Impact factor: 12.988

2.  A GRIM fate for human neutrophils in airway disease.

Authors:  Thomas C Mitchell
Journal:  J Leukoc Biol       Date:  2018-08-01       Impact factor: 4.962

Review 3.  Embracing microbial exposure in mouse research.

Authors:  Mathew A Huggins; Stephen C Jameson; Sara E Hamilton
Journal:  J Leukoc Biol       Date:  2018-09-27       Impact factor: 4.962

4.  Leaking chemokines confuse neutrophils.

Authors:  Alex Marki; Klaus Ley
Journal:  J Clin Invest       Date:  2020-05-01       Impact factor: 14.808

5.  Reply to Fattori et al.: Action of SP and IL-33 on mast cells.

Authors:  Theoharis C Theoharides; Alexandra Taracanova; Irene Tsilioni; Pio Conti; Susan E Leeman
Journal:  Proc Natl Acad Sci U S A       Date:  2017-11-06       Impact factor: 11.205

Review 6.  Sepsis-Induced T Cell Immunoparalysis: The Ins and Outs of Impaired T Cell Immunity.

Authors:  Isaac J Jensen; Frances V Sjaastad; Thomas S Griffith; Vladimir P Badovinac
Journal:  J Immunol       Date:  2018-03-01       Impact factor: 5.422

7.  Combined immunodeficiency due to a mutation in the γ1 subunit of the coat protein I complex.

Authors:  Wayne Bainter; Craig D Platt; Seung-Yeol Park; Kelsey Stafstrom; Jacqueline G Wallace; Zachary T Peters; Michel J Massaad; Michel Becuwe; Sandra Andrea Salinas; Jennifer Jones; Sarah Beaussant-Cohen; Faris Jaber; Jia-Shu Yang; Tobias C Walther; Jordan S Orange; Chitong Rao; Seth Rakoff-Nahoum; Maria Tsokos; Shafiq Ur Rehman Naseem; Salem Al-Tamemi; Janet Chou; Victor W Hsu; Raif S Geha
Journal:  J Clin Invest       Date:  2021-02-01       Impact factor: 14.808

Review 8.  New Insights into the Immune System Using Dirty Mice.

Authors:  Sara E Hamilton; Vladimir P Badovinac; Lalit K Beura; Mark Pierson; Stephen C Jameson; David Masopust; Thomas S Griffith
Journal:  J Immunol       Date:  2020-07-01       Impact factor: 5.422

9.  Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization.

Authors:  Matthew A Huggins; Frances V Sjaastad; Mark Pierson; Tamara A Kucaba; Whitney Swanson; Christopher Staley; Alexa R Weingarden; Isaac J Jensen; Derek B Danahy; Vladimir P Badovinac; Stephen C Jameson; Vaiva Vezys; David Masopust; Alexander Khoruts; Thomas S Griffith; Sara E Hamilton
Journal:  Cell Rep       Date:  2019-08-13       Impact factor: 9.423

Review 10.  Age-related susceptibility to coronavirus infections: role of impaired and dysregulated host immunity.

Authors:  Rudragouda Channappanavar; Stanley Perlman
Journal:  J Clin Invest       Date:  2020-12-01       Impact factor: 14.808
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