Literature DB >> 28694308

Association of delay of urgent or emergency surgery with mortality and use of health care resources: a propensity score-matched observational cohort study.

Daniel I McIsaac1, Karim Abdulla2, Homer Yang2, Sudhir Sundaresan2, Paula Doering2, Sandeep Green Vaswani2, Kednapa Thavorn2, Alan J Forster2.   

Abstract

BACKGROUND: Delay of surgery for hip fracture is associated with increased risk of morbidity and mortality, but the effects of surgical delays on mortality and resource use in the context of other emergency surgeries is poorly described. Our objective was to measure the independent association between delay of emergency surgery and in-hospital mortality, length of stay and costs.
METHODS: We identified all adult patients who underwent emergency noncardiac surgery between January 2012 and October 2014 at a single tertiary care centre. Delay of surgery was defined as the time from surgical booking to operating room entry exceeding institutionally defined acceptable wait times, based on a standardized 5-level priority system that accounted for surgery type and indication. Patients with delayed surgery were matched to those without delay using propensity scores derived from variables that accounted for details of admission and the hospital stay, patient characteristics, physiologic instability, and surgical urgency and risk.
RESULTS: Of 15 160 patients, 2820 (18.6%) experienced a delay. The mortality rates were 4.9% (138/2820) for those with delay and 3.2% (391/12 340) for those without delay (odds ratio [OR] 1.59, 95% confidence interval [CI] 1.30-1.93). Within the propensity-matched cohort, delay was significantly associated with mortality (OR 1.56, 95% CI 1.18-2.06), increased length of stay (incident rate ratio 1.07, 95% CI 1.01-1.11) and higher total costs (incident rate ratio 1.06, 95% CI 1.01-1.11).
INTERPRETATION: Delayed operating room access for emergency surgery was associated with increased risk of inhospital mortality, longer length of stay and higher costs. System issues appeared to underlie most delays and must be addressed to improve the outcomes of emergency surgery.
© 2017 Canadian Medical Association or its licensors.

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Year:  2017        PMID: 28694308      PMCID: PMC5505757          DOI: 10.1503/cmaj.160576

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  28 in total

Review 1.  Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis.

Authors:  Nicole Simunovic; P J Devereaux; Sheila Sprague; Gordon H Guyatt; Emil Schemitsch; Justin Debeer; Mohit Bhandari
Journal:  CMAJ       Date:  2010-09-13       Impact factor: 8.262

2.  A case-control study investigating factors of preoperative delay in emergency laparotomy.

Authors:  Crispin Schneider; Laura E Tyler; Eleanor F Scull; Belinda J Pryle; Hugh Barr
Journal:  Int J Surg       Date:  2015-08-28       Impact factor: 6.071

Review 3.  A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003.

Authors:  Peter C Austin
Journal:  Stat Med       Date:  2008-05-30       Impact factor: 2.373

4.  Surgical delay is a critical determinant of survival in perforated peptic ulcer.

Authors:  D L Buck; M Vester-Andersen; M H Møller
Journal:  Br J Surg       Date:  2013-07       Impact factor: 6.939

5.  Effect of delay to operation on outcomes in adults with acute appendicitis.

Authors:  Angela M Ingraham; Mark E Cohen; Karl Y Bilimoria; Clifford Y Ko; Bruce L Hall; Thomas R Russell; Avery B Nathens
Journal:  Arch Surg       Date:  2010-09

6.  Risk-adjusting hospital inpatient mortality using automated inpatient, outpatient, and laboratory databases.

Authors:  Gabriel J Escobar; John D Greene; Peter Scheirer; Marla N Gardner; David Draper; Patricia Kipnis
Journal:  Med Care       Date:  2008-03       Impact factor: 2.983

7.  Re-engineering the operating room using variability methodology to improve health care value.

Authors:  C Daniel Smith; Thomas Spackman; Karen Brommer; Michael W Stewart; Michael Vizzini; James Frye; William C Rupp
Journal:  J Am Coll Surg       Date:  2013-04       Impact factor: 6.113

8.  The public health burden of emergency general surgery in the United States: A 10-year analysis of the Nationwide Inpatient Sample--2001 to 2010.

Authors:  Stephen C Gale; Shahid Shafi; Viktor Y Dombrovskiy; Dena Arumugam; Jessica S Crystal
Journal:  J Trauma Acute Care Surg       Date:  2014-08       Impact factor: 3.313

9.  Allocating operating room resources to an acute care surgery service does not affect wait-times for elective cancer surgeries: a retrospective cohort study.

Authors:  Ram Venkatesh Anantha; Dave Paskar; Kelly Vogt; Silvie Crawford; Neil Parry; Ken Leslie
Journal:  World J Emerg Surg       Date:  2014-03-27       Impact factor: 5.469

10.  Time from admission to initiation of surgery for source control is a critical determinant of survival in patients with gastrointestinal perforation with associated septic shock.

Authors:  Takeo Azuhata; Kosaku Kinoshita; Daisuke Kawano; Tomonori Komatsu; Atsushi Sakurai; Yasutaka Chiba; Katsuhisa Tanjho
Journal:  Crit Care       Date:  2014-05-02       Impact factor: 9.097

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  31 in total

1.  Association Between Wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery.

Authors:  Daniel Pincus; Bheeshma Ravi; David Wasserstein; Anjie Huang; J Michael Paterson; Avery B Nathens; Hans J Kreder; Richard J Jenkinson; Walter P Wodchis
Journal:  JAMA       Date:  2017-11-28       Impact factor: 56.272

2.  District General Hospital Surgical Capacity and Mortality Trends in Patients with Acute Abdomen in Malawi.

Authors:  Laura N Purcell; Brittany Robinson; Vanessa Msosa; Jared Gallaher; Anthony Charles
Journal:  World J Surg       Date:  2020-07       Impact factor: 3.352

3.  Delivering timely surgery in Canadian hospitals.

Authors:  David R Urbach
Journal:  CMAJ       Date:  2017-07-10       Impact factor: 8.262

4.  Focus on saving money lets patients and surgeons down.

Authors:  Gustavo Azoubel
Journal:  CMAJ       Date:  2018-10-01       Impact factor: 8.262

5.  Mortality effects of timing alternatives for hip fracture surgery.

Authors:  Boris Sobolev; Pierre Guy; Katie Jane Sheehan; Lisa Kuramoto; Jason M Sutherland; Adrian R Levy; James A Blair; Eric Bohm; Jason D Kim; Edward J Harvey; Suzanne N Morin; Lauren Beaupre; Michael Dunbar; Susan Jaglal; James Waddell
Journal:  CMAJ       Date:  2018-08-07       Impact factor: 8.262

6.  Urgent care access: finding solutions that match causation.

Authors:  Paul E Beaule; Sudhir Nagpal; Fady Balaa; Sudhir Sundaresan
Journal:  CMAJ       Date:  2018-01-15       Impact factor: 8.262

7.  Timing and Outcomes of Abdominal Surgery in Neutropenic Patients.

Authors:  Joshua S Jolissaint; Maya Harary; Lily V Saadat; Arin L Madenci; Bryan V Dieffenbach; Riad H Al Natour; Ali Tavakkoli
Journal:  J Gastrointest Surg       Date:  2019-01-18       Impact factor: 3.452

8.  Predictors of mortality and cost among surgical patients requiring rapid response team activation.

Authors:  Alexandre Tran; Shannon M Fernando; Daniel I McIsaac; Bram Rochwerg; Garrick Mok; Andrew J E Seely; Dalibor Kubelik; Kenji Inaba; Dennis Y Kim; Peter M Reardon; Jennifer Shen; Peter Tanuseputro; Kednapa Thavorn; Kwadwo Kyeremanteng
Journal:  Can J Surg       Date:  2020-12-09       Impact factor: 2.089

9.  Effect of Time to Operation on Value of Care in Acute Care Surgery.

Authors:  Tyler J Loftus; Martin D Rosenthal; Chasen A Croft; R Stephen Smith; Philip A Efron; Frederick A Moore; Alicia M Mohr; Scott C Brakenridge
Journal:  World J Surg       Date:  2018-08       Impact factor: 3.352

10.  Mortality rates of patients undergoing emergency laparotomy in an Irish university teaching hospital.

Authors:  Aoife C Kiernan; Peadar S Waters; Sean Tierney; Paul Neary; Maria Donnelly; Dara O Kavanagh; Bridget Egan
Journal:  Ir J Med Sci       Date:  2018-02-15       Impact factor: 1.568

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