Literature DB >> 28694251

Advances in the causes and management of community acquired pneumonia in adults.

Richard G Wunderink1, Grant Waterer2,3.   

Abstract

Community acquired pneumonia remains a common cause of morbidity and mortality. Usually, the causal organism is not identified and treatment remains empiric. Recent computed tomography and magnetic resonance imaging studies have challenged the accuracy of the clinical diagnosis of pneumonia, and epidemiologic studies are changing our perspective of what causes community acquired pneumonia, especially the role of viral pathogens and the frequent finding of multiple pathogens. The past decade has seen increasing overuse of empiric coverage of meticillin resistant Staphylococcus aureus and antibiotic resistant Gram negative pathogens owing to inappropriate application of guidelines for healthcare associated pneumonia. Optimal treatment remains a matter for debate, especially in very sick patients, including the role of combination antibiotic therapy and corticosteroids. Pneumonia care bundles are being defined to improve outcomes. Increased recognition of both acute and long term cardiac complications is shifting our concept of pneumonia from an acute lung disease to a multisystem problem with adverse chronic health consequences. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

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Year:  2017        PMID: 28694251     DOI: 10.1136/bmj.j2471

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  43 in total

Review 1.  Older but Not Wiser: the Age-Driven Changes in Neutrophil Responses during Pulmonary Infections.

Authors:  Shaunna R Simmons; Manmeet Bhalla; Sydney E Herring; Essi Y I Tchalla; Elsa N Bou Ghanem
Journal:  Infect Immun       Date:  2021-03-17       Impact factor: 3.441

2.  Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation.

Authors:  Sebastián A Riquelme; Kalle Liimatta; Tania Wong Fok Lung; Blanche Fields; Danielle Ahn; David Chen; Carmen Lozano; Yolanda Sáenz; Anne-Catrin Uhlemann; Barbara C Kahl; Clemente J Britto; Emily DiMango; Alice Prince
Journal:  Cell Metab       Date:  2020-05-18       Impact factor: 27.287

3.  Rapid Detection of Methicillin-Resistant Staphylococcus aureus in BAL: A Pilot Randomized Controlled Trial.

Authors:  Joseph R Paonessa; Raj D Shah; Chiagozie I Pickens; Bryan D Lizza; Helen K Donnelly; Michael Malczynski; Chao Qi; Richard G Wunderink
Journal:  Chest       Date:  2019-02-15       Impact factor: 9.410

4.  Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.

Authors:  Jie Tian; Xiao-Long Wang; Long-Cheng Wang; Fei Chen; Yun Tian; Li Ma; Chao-Yun Pan; Yan-Ping Wang
Journal:  Pharm Biol       Date:  2022-12       Impact factor: 3.889

5.  Association of Vitamin D Status with the Severity and Mortality of Community-Acquired Pneumonia in Iran during 2016-2017: A Prospective Cohort Study.

Authors:  Fatemeh Talebi; Mehrnaz Rasooli Nejad; Mehdi Yaseri; Azar Hadadi
Journal:  Rep Biochem Mol Biol       Date:  2019-04

6.  Evaluation of pulmonary B lines by different intensive care physicians using bedside ultrasonography: a reliability study.

Authors:  Juliana Rodrigues Vieira; Marcela Rangel de Castro; Thaís de Paula Guimarães; Aldo José Tavarez Pinheiro; Ana Clara Tiso Costa Figueiredo; Bruna Jacomini Martins; Daniel Reis do Carmo; Wesley Academes Oliveira
Journal:  Rev Bras Ter Intensiva       Date:  2019-10-14

7.  The Role of Pneumococcal Pneumonia among Community-Acquired Pneumonia in Adult Turkish Population: TurkCAP Study.

Authors:  Esin Şenol; Aykut Çilli; Hakan Günen; Alper Şener; Rıdvan Dumlu; Ayşe Ödemiş; Ayşe Füsun Topçu; Yeşim Yıldız; Rahmet Güner; Ayhan Özhasenekler; Birsen Mutlu; Nurdan Köktürk; Nurgül Sevimli; Nurcan Baykam; Derya Yapar; Selami Ekin; Mehmet Polatlı; Şebnem Eren Gök; Oğuz Kılınç; Abdullah Sayıner; Ömer Karaşahin; Çağlar Çuhadaroğlu; Ayşe Sesin Kocagöz; Turhan Togan; Hüseyin Arpağ; Hakan Katı; İftihar Köksal; Firdevs Aksoy; Canan Hasanoğlu
Journal:  Turk Thorac J       Date:  2021-07

Review 8.  Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease.

Authors:  William Walkowski; Justin Bassett; Manmeet Bhalla; Blaine A Pfeifer; Elsa N Bou Ghanem
Journal:  Vaccines (Basel)       Date:  2021-06-02

Review 9.  Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome.

Authors:  Joshua A Englert; Christopher Bobba; Rebecca M Baron
Journal:  JCI Insight       Date:  2019-01-24

10.  Transcriptome Profiling Reveals CD73 and Age-Driven Changes in Neutrophil Responses against Streptococcus pneumoniae.

Authors:  Manmeet Bhalla; Lauren R Heinzinger; Olanrewaju B Morenikeji; Brandon Marzullo; Bolaji N Thomas; Elsa N Bou Ghanem
Journal:  Infect Immun       Date:  2021-07-26       Impact factor: 3.609

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