Joséphine Bryere1, Gwenn Menvielle2, Olivier Dejardin3, Ludivine Launay3, Florence Molinie4, Isabelle Stucker5, Daniele Luce6, Guy Launoy3. 1. "Cancers & Préventions" U1086 INSERM-UCN, Team Labeled « Ligue Contre le Cancer », Centre François Baclesse, Avenue Général Harris, 14076 Caen, France. Electronic address: josephine.bryere@inserm.fr. 2. Sorbonne Université, UPMC Univ Paris 6, INSERM, Institut Pierre Louis d'Epidémiologie et Santé Publique (IPLESP UMRS 1136) 75012 Paris, France. 3. "Cancers & Préventions" U1086 INSERM-UCN, Team Labeled « Ligue Contre le Cancer », Centre François Baclesse, Avenue Général Harris, 14076 Caen, France. 4. Registre des Cancers de Loire-Atlantique et Vendée, 50 route de Saint-Sébastien, 44093 Nantes Cedex 1, France. 5. INSERM UMRS 1018, Centre de Recherche en Epidémiologie et santé des Populations, 15/16 Avenue Paul Vaillant Couturier, 94807 Villejuif, France. 6. INSERM U1085, IRSET, Faculté de Médecine, Campus de Fouillole 97154 Point-à-Pitre, France.
Abstract
BACKGROUND: While it is known that cancer risk is related to area-level socioeconomic status, the extent to which these inequalities are explained by contextual effects is poorly documented especially for head and neck cancer. METHODS: A case-control study, ICARE, included 2415 head and neck cancer cases and 3555 controls recruited between 2001 and 2007 from 10 French regions retrieved from a general cancer registry. Individual socioeconomic status was assessed using marital status, highest educational level and occupational social class. Area-level socioeconomic status was assessed using the French version of the European Deprivation Index (EDI). The relationship between both individual and area-based socioeconomic level and the risk of head and neck cancer was assessed by multilevel analyses. RESULTS: A higher risk for head and neck cancer was found in divorced compared with married individuals (OR=2.14, 95% CI=1.78-2.57), for individuals with a basic school-leaving qualification compared with those with higher education (OR=4.55 95% CI=3.72-5.57), for manual workers compared with managers (OR=4.91, 95% CI=3.92-6.15) and for individuals living in the most deprived areas compared with those living in the most affluent ones (OR=1.98, 95% CI=1.64-2.41). The influence of area-level socioeconomic status measured by EDI remained after controlling for individual socioeconomic characteristics (OR=1.51; 95% confidence interval: 1.23-1.85, p-value=0.0003). CONCLUSIONS: The role of individual socioeconomic status in the risk of head and neck cancer is undeniable, although contextual effects of deprived areas also increase the susceptibility of individuals developing the disease.
BACKGROUND: While it is known that cancer risk is related to area-level socioeconomic status, the extent to which these inequalities are explained by contextual effects is poorly documented especially for head and neck cancer. METHODS: A case-control study, ICARE, included 2415 head and neck cancer cases and 3555 controls recruited between 2001 and 2007 from 10 French regions retrieved from a general cancer registry. Individual socioeconomic status was assessed using marital status, highest educational level and occupational social class. Area-level socioeconomic status was assessed using the French version of the European Deprivation Index (EDI). The relationship between both individual and area-based socioeconomic level and the risk of head and neck cancer was assessed by multilevel analyses. RESULTS: A higher risk for head and neck cancer was found in divorced compared with married individuals (OR=2.14, 95% CI=1.78-2.57), for individuals with a basic school-leaving qualification compared with those with higher education (OR=4.55 95% CI=3.72-5.57), for manual workers compared with managers (OR=4.91, 95% CI=3.92-6.15) and for individuals living in the most deprived areas compared with those living in the most affluent ones (OR=1.98, 95% CI=1.64-2.41). The influence of area-level socioeconomic status measured by EDI remained after controlling for individual socioeconomic characteristics (OR=1.51; 95% confidence interval: 1.23-1.85, p-value=0.0003). CONCLUSIONS: The role of individual socioeconomic status in the risk of head and neck cancer is undeniable, although contextual effects of deprived areas also increase the susceptibility of individuals developing the disease.
Authors: Anastasia Zelenina; Svetlana Shalnova; Sergey Maksimov; Oksana Drapkina Journal: Int J Environ Res Public Health Date: 2022-08-15 Impact factor: 4.614
Authors: Fiona C Ingleby; Aurélien Belot; Iain Atherton; Matthew Baker; Lucy Elliss-Brookes; Laura M Woods Journal: BMJ Open Date: 2020-11-26 Impact factor: 2.692