Chao Chen1, Qinqin Kang2, Bing Xu2, Hairuo Guo3, Qiang Wei4, Tiegong Wang2, Hui Ye5, Xinhuai Wu6. 1. Department of Radiology, PLA Army General Hospital, Beijing 100700, China. 2. Department of Radiology, Changhai Hospital of Shanghai, The second Military Medical University, Shanghai 200433, China. 3. Affiliated Bayi Brain Hospital, PLA Army General Hospital, Beijing 100700, China. 4. Department of Orthopaedics, Changhai Hospital of Shanghai, The second Military Medical University, Shanghai 200433, China. 5. Hunan Tumor Hospital, PET-CT Center, Changsha 410013, China. 6. Department of Radiology, PLA Army General Hospital, Beijing 100700, China. Electronic address: wuxinhuai_beijing@163.com.
Abstract
PURPOSE: To compare the utility of tumor size and CT perfusion parameters for differentiation of low- and high-grade clear cell renal cell carcinoma (RCC). MATERIALS AND METHODS: Tumor size, Equivalent blood volume (Equiv BV), permeability surface-area product (PS), blood flow (BF), and Fuhrman pathological grading of clear cell RCC were retrospectively analyzed. RESULTS: High-grade clear cell RCC had significantly higher tumor size and lower PS than low grade. Tumor size positively correlated with Fuhrman grade, but PS negatively did. CONCLUSIONS: Tumor size and PS were significantly independent indexes for differentiating high-grade from low-grade clear cell RCC.
PURPOSE: To compare the utility of tumor size and CT perfusion parameters for differentiation of low- and high-grade clear cell renal cell carcinoma (RCC). MATERIALS AND METHODS:Tumor size, Equivalent blood volume (Equiv BV), permeability surface-area product (PS), blood flow (BF), and Fuhrman pathological grading of clear cell RCC were retrospectively analyzed. RESULTS: High-grade clear cell RCC had significantly higher tumor size and lower PS than low grade. Tumor size positively correlated with Fuhrman grade, but PS negatively did. CONCLUSIONS:Tumor size and PS were significantly independent indexes for differentiating high-grade from low-grade clear cell RCC.