| Literature DB >> 28684525 |
Raz Avni1, Moran Nave1, Omer Barad2, Kobi Baruch2, Sven O Twardziok3, Heidrun Gundlach3, Iago Hale4, Martin Mascher5,6, Manuel Spannagl3, Krystalee Wiebe7, Katherine W Jordan8, Guy Golan9, Jasline Deek1, Batsheva Ben-Zvi1, Gil Ben-Zvi2, Axel Himmelbach10, Ron P MacLachlan7, Andrew G Sharpe7,11, Allan Fritz8, Roi Ben-David12, Hikmet Budak13, Tzion Fahima14, Abraham Korol14, Justin D Faris15, Alvaro Hernandez16, Mark A Mikel16, Avraham A Levy17, Brian Steffenson18, Marco Maccaferri19, Roberto Tuberosa19, Luigi Cattivelli20, Primetta Faccioli20, Aldo Ceriotti21, Khalil Kashkush22, Mohammad Pourkheirandish23, Takao Komatsuda24, Tamar Eilam25, Hanan Sela25, Amir Sharon1,25, Nir Ohad1, Daniel A Chamovitz1, Klaus F X Mayer3,26, Nils Stein10, Gil Ronen2, Zvi Peleg9, Curtis J Pozniak7, Eduard D Akhunov8, Assaf Distelfeld1,25.
Abstract
Wheat (Triticum spp.) is one of the founder crops that likely drove the Neolithic transition to sedentary agrarian societies in the Fertile Crescent more than 10,000 years ago. Identifying genetic modifications underlying wheat's domestication requires knowledge about the genome of its allo-tetraploid progenitor, wild emmer (T. turgidum ssp. dicoccoides). We report a 10.1-gigabase assembly of the 14 chromosomes of wild tetraploid wheat, as well as analyses of gene content, genome architecture, and genetic diversity. With this fully assembled polyploid wheat genome, we identified the causal mutations in Brittle Rachis 1 (TtBtr1) genes controlling shattering, a key domestication trait. A study of genomic diversity among wild and domesticated accessions revealed genomic regions bearing the signature of selection under domestication. This reference assembly will serve as a resource for accelerating the genome-assisted improvement of modern wheat varieties.Entities:
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Year: 2017 PMID: 28684525 DOI: 10.1126/science.aan0032
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728