Literature DB >> 28683280

Ancillary Activity: Beyond Core Metabolism in Immune Cells.

Daniel J Puleston1, Matteo Villa2, Erika L Pearce3.   

Abstract

Immune cell function and fate are intimately linked to engagement of metabolic pathways. The contribution of core metabolic pathways to immune cell bioenergetics has been vigorously investigated in recent years. However, precisely how other peripheral metabolic pathways support immune cells beyond energy generation is less well understood. Here we survey the literature and highlight recent advances in our understanding of several ancillary metabolic pathways and how they support processes beyond ATP production and ultimately contribute to protective immunity.
Copyright © 2017. Published by Elsevier Inc.

Entities:  

Keywords:  O-GlcNAcylation; cholesterol; hexosamine synthesis pathway; immune cell metabolism; immunity; metabolism; nucleotides; one-carbon metabolism; pentose phosphate pathway; polyamines

Mesh：

Substances：

Year:  2017        PMID： 28683280      PMCID： PMC5546226          DOI： 10.1016/j.cmet.2017.06.019

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  93 in total

1.  Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

Authors:  Autumn G York; Kevin J Williams; Joseph P Argus; Quan D Zhou; Gurpreet Brar; Laurent Vergnes; Elizabeth E Gray; Anjie Zhen; Nicholas C Wu; Douglas H Yamada; Cameron R Cunningham; Elizabeth J Tarling; Moses Q Wilks; David Casero; David H Gray; Amy K Yu; Eric S Wang; David G Brooks; Ren Sun; Scott G Kitchen; Ting-Ting Wu; Karen Reue; Daniel B Stetson; Steven J Bensinger
Journal:  Cell       Date:  2015-12-10       Impact factor: 41.582

2.  The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny.

Authors:  R Shafi; S P Iyer; L G Ellies; N O'Donnell; K W Marek; D Chui; G W Hart; J D Marth
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

3.  Induction of ornithine decarboxylase by IL-3 is mediated by sequential c-Myc-independent and c-Myc-dependent pathways.

Authors:  G Packham; J L Cleveland
Journal:  Oncogene       Date:  1997-09-04       Impact factor: 9.867

4.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Authors:  Ruoning Wang; Christopher P Dillon; Lewis Zhichang Shi; Sandra Milasta; Robert Carter; David Finkelstein; Laura L McCormick; Patrick Fitzgerald; Hongbo Chi; Joshua Munger; Douglas R Green
Journal:  Immunity       Date:  2011-12-23       Impact factor: 31.745

5.  c-Myc induces the expression and activity of ornithine decarboxylase.

Authors:  A J Wagner; C Meyers; L A Laimins; N Hay
Journal:  Cell Growth Differ       Date:  1993-11

6.  T cell receptor signaling co-regulates multiple Golgi genes to enhance N-glycan branching.

Authors:  Hung-Lin Chen; Carey Fei Li; Ani Grigorian; Wenqiang Tian; Michael Demetriou
Journal:  J Biol Chem       Date:  2009-08-25       Impact factor: 5.157

7.  A fluorescent probe of polyamine transport accumulates into intracellular acidic vesicles via a two-step mechanism.

Authors:  Denis Soulet; Bruno Gagnon; Serge Rivest; Marie Audette; Richard Poulin
Journal:  J Biol Chem       Date:  2004-06-17       Impact factor: 5.157

8.  De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

Authors:  Luciana Berod; Christin Friedrich; Amrita Nandan; Jenny Freitag; Stefanie Hagemann; Kirsten Harmrolfs; Aline Sandouk; Christina Hesse; Carla N Castro; Heike Bähre; Sarah K Tschirner; Nataliya Gorinski; Melanie Gohmert; Christian T Mayer; Jochen Huehn; Evgeni Ponimaskin; Wolf-Rainer Abraham; Rolf Müller; Matthias Lochner; Tim Sparwasser
Journal:  Nat Med       Date:  2014-10-05       Impact factor: 53.440

9.  Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism.

Authors:  Antonio Castrillo; Sean B Joseph; Sagar A Vaidya; Margaret Haberland; Alan M Fogelman; Genhong Cheng; Peter Tontonoz
Journal:  Mol Cell       Date:  2003-10       Impact factor: 17.970

10.  The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

Authors:  Mathieu Blanc; Wei Yuan Hsieh; Kevin A Robertson; Kai A Kropp; Thorsten Forster; Guanghou Shui; Paul Lacaze; Steven Watterson; Samantha J Griffiths; Nathanael J Spann; Anna Meljon; Simon Talbot; Kathiresan Krishnan; Douglas F Covey; Markus R Wenk; Marie Craigon; Zsolts Ruzsics; Jürgen Haas; Ana Angulo; William J Griffiths; Christopher K Glass; Yuqin Wang; Peter Ghazal
Journal:  Immunity       Date:  2012-12-27       Impact factor: 31.745
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  39 in total

Review 1.  HIV Persistence in Adipose Tissue Reservoirs.

Authors:  Jacob Couturier; Dorothy E Lewis
Journal:  Curr HIV/AIDS Rep       Date:  2018-02       Impact factor: 5.071

2.  Immunometabolism in 2017: Driving immunity: all roads lead to metabolism.

Authors:  Edward J Pearce; Erika L Pearce
Journal:  Nat Rev Immunol       Date:  2017-12-11       Impact factor: 53.106

3.  CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight Into Reduced Cardiovascular Risk Associated With Mediterranean G6PD Variant.

Authors:  Atsushi Kitagawa; Igor Kizub; Christina Jacob; Kevin Michael; Angelo D'Alessandro; Julie A Reisz; Michael Grzybowski; Aron M Geurts; Petra Rocic; Rakhee Gupte; Joseph M Miano; Sachin A Gupte
Journal:  Hypertension       Date:  2020-06-08       Impact factor: 10.190

4.  Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis.

Authors:  Patrycja Puchalska; Shannon E Martin; Xiaojing Huang; Justin E Lengfeld; Bence Daniel; Mark J Graham; Xianlin Han; Laszlo Nagy; Gary J Patti; Peter A Crawford
Journal:  Cell Metab       Date:  2018-11-15       Impact factor: 27.287

Review 5.  Unraveling the Complex Interplay Between T Cell Metabolism and Function.

Authors:  Ramon I Klein Geltink; Ryan L Kyle; Erika L Pearce
Journal:  Annu Rev Immunol       Date:  2018-04-26       Impact factor: 28.527

6.  Acetate Promotes T Cell Effector Function during Glucose Restriction.

Authors:  Jing Qiu; Matteo Villa; David E Sanin; Michael D Buck; David O'Sullivan; Reagan Ching; Mai Matsushita; Katarzyna M Grzes; Frances Winkler; Chih-Hao Chang; Jonathan D Curtis; Ryan L Kyle; Nikki Van Teijlingen Bakker; Mauro Corrado; Fabian Haessler; Francesca Alfei; Joy Edwards-Hicks; Leonard B Maggi; Dietmar Zehn; Takeshi Egawa; Bertram Bengsch; Ramon I Klein Geltink; Thomas Jenuwein; Edward J Pearce; Erika L Pearce
Journal:  Cell Rep       Date:  2019-05-14       Impact factor: 9.423

7.  Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.

Authors:  Sachindra Raj Joshi; Atsushi Kitagawa; Christina Jacob; Ryota Hashimoto; Vidhi Dhagia; Amrit Ramesh; Connie Zheng; Hui Zhang; Allan Jordan; Ian Waddell; Jane Leopold; Cheng-Jun Hu; Ivan F McMurtry; Angelo D'Alessandro; Kurt R Stenmark; Sachin A Gupte
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2020-03-11       Impact factor: 5.464

8.  Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation.

Authors:  Pavan Bhargava; Matthew D Smith; Leah Mische; Emily Harrington; Kathryn C Fitzgerald; Kyle Martin; Sol Kim; Arthur Anthony Reyes; Jaime Gonzalez-Cardona; Christina Volsko; Ajai Tripathi; Sonal Singh; Kesava Varanasi; Hannah-Noelle Lord; Keya Meyers; Michelle Taylor; Marjan Gharagozloo; Elias S Sotirchos; Bardia Nourbakhsh; Ranjan Dutta; Ellen M Mowry; Emmanuelle Waubant; Peter A Calabresi
Journal:  J Clin Invest       Date:  2020-07-01       Impact factor: 14.808

Review 9.  Metabolism as a guiding force for immunity.

Authors:  Jonathan Jung; Hu Zeng; Tiffany Horng
Journal:  Nat Cell Biol       Date:  2019-01-02       Impact factor: 28.824

Review 10.  Metabolic Strategies for Inhibiting Cancer Development.

Authors:  Philippe Icard; Mauro Loi; Zherui Wu; Antonin Ginguay; Hubert Lincet; Edouard Robin; Antoine Coquerel; Diana Berzan; Ludovic Fournel; Marco Alifano
Journal:  Adv Nutr       Date:  2021-07-30       Impact factor: 8.701
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