Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Mild Cobalt(III)-Catalyzed Allylative C-F/C-H Functionalizations at Room Temperature.

Literature DB >> 28675487

Mild Cobalt(III)-Catalyzed Allylative C-F/C-H Functionalizations at Room Temperature.

Daniel Zell¹, Valentin Müller¹, Uttam Dhawa¹, Markus Bursch², Rubén Rubio Presa¹, Stefan Grimme², Lutz Ackermann¹.

Abstract

Sustainable, cobalt-catalyst enabled, synthetically significant C-F/C-H functionalizations were achieved with an ample substrate scope at an ambient temperature of 25 °C, thereby delivering perfluoroallylated heteroarenes. Detailed experimental and computational mechanistic studies on the C-F/C-H functionalizations provided strong support for a facile C-F cleavage.

Entities: Chemical

Keywords: C−H activation; cobalt; mild conditions; reaction mechanisms; β-fluorine elimination

Year: 2017 PMID： 28675487 DOI： 10.1002/chem.201702528

Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236

Keyword Cloud
Cited

7 in total

1. Recent Advances in Transition Metal-Catalyzed Functionalization of gem-Difluoroalkenes.

Authors: Suvajit Koley; Ryan A Altman
Journal: Isr J Chem Date: 2020-03-10 Impact factor: 3.333

Review 2. A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

Authors: Carlo Sambiagio; David Schönbauer; Remi Blieck; Toan Dao-Huy; Gerit Pototschnig; Patricia Schaaf; Thomas Wiesinger; Muhammad Farooq Zia; Joanna Wencel-Delord; Tatiana Besset; Bert U W Maes; Michael Schnürch
Journal: Chem Soc Rev Date: 2018-08-28 Impact factor: 54.564

3. Rhodium-Catalyzed Merging of 2-Arylquinazolinone and 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Monofluoroolefin Quinazolinone Derivatives.

Authors: Ning Wang; Qin Yang; Zhihong Deng; Xuechun Mao; Yiyuan Peng
Journal: ACS Omega Date: 2020-06-15

Mild Cobalt(III)-Catalyzed Allylative C-F/C-H Functionalizations at Room Temperature.

1. Recent Advances in Transition Metal-Catalyzed Functionalization of gem-Difluoroalkenes.

Review 2. A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

3. Rhodium-Catalyzed Merging of 2-Arylquinazolinone and 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Monofluoroolefin Quinazolinone Derivatives.

4. Monoallylation and benzylation of dicarbonyl compounds with alcohols catalysed by a cationic cobalt(iii) compound.

5. Synergistic Pd/Cu-catalyzed enantioselective Csp²-F bond alkylation of fluoro-1,3-dienes with aldimine esters.

6. Arylation of gem-difluoroalkenes using a Pd/Cu Co-catalytic system that avoids β-fluoride elimination.

7. Thiocarbonyl-enabled ferrocene C-H nitrogenation by cobalt(III) catalysis: thermal and mechanochemical.

Mild Cobalt(III)-Catalyzed Allylative C-F/C-H Functionalizations at Room Temperature.

1. Recent Advances in Transition Metal-Catalyzed Functionalization of gem-Difluoroalkenes.

Review 2. A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

3. Rhodium-Catalyzed Merging of 2-Arylquinazolinone and 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Monofluoroolefin Quinazolinone Derivatives.

4. Monoallylation and benzylation of dicarbonyl compounds with alcohols catalysed by a cationic cobalt(iii) compound.

5. Synergistic Pd/Cu-catalyzed enantioselective Csp2-F bond alkylation of fluoro-1,3-dienes with aldimine esters.

6. Arylation of gem-difluoroalkenes using a Pd/Cu Co-catalytic system that avoids β-fluoride elimination.

7. Thiocarbonyl-enabled ferrocene C-H nitrogenation by cobalt(III) catalysis: thermal and mechanochemical.

5. Synergistic Pd/Cu-catalyzed enantioselective Csp²-F bond alkylation of fluoro-1,3-dienes with aldimine esters.