Literature DB >> 28669986

Mitochondrial control of immunity: beyond ATP.

Manan M Mehta1, Samuel E Weinberg1, Navdeep S Chandel1.   

Abstract

Mitochondria are important signalling organelles, and they dictate immunological fate. From T cells to macrophages, mitochondria form the nexus of the various metabolic pathways that define each immune cell subset. In this central position, mitochondria help to control the various metabolic decision points that determine immune cell function. In this Review, we discuss how mitochondrial metabolism varies across different immune cell subsets, how metabolic signalling dictates cell fate and how this signalling could potentially be targeted therapeutically.

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Year:  2017        PMID： 28669986     DOI： 10.1038/nri.2017.66

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  125 in total

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Authors:  Haiyan Tan; Kai Yang; Yuxin Li; Timothy I Shaw; Yanyan Wang; Daniel Bastardo Blanco; Xusheng Wang; Ji-Hoon Cho; Hong Wang; Sherri Rankin; Cliff Guy; Junmin Peng; Hongbo Chi
Journal:  Immunity       Date:  2017-03-09       Impact factor: 31.745

4.  Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.

Authors:  Valerie A Gerriets; Rigel J Kishton; Amanda G Nichols; Andrew N Macintyre; Makoto Inoue; Olga Ilkayeva; Peter S Winter; Xiaojing Liu; Bhavana Priyadharshini; Marta E Slawinska; Lea Haeberli; Catherine Huck; Laurence A Turka; Kris C Wood; Laura P Hale; Paul A Smith; Martin A Schneider; Nancie J MacIver; Jason W Locasale; Christopher B Newgard; Mari L Shinohara; Jeffrey C Rathmell
Journal:  J Clin Invest       Date:  2014-12-01       Impact factor: 14.808

5.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Authors:  Ruoning Wang; Christopher P Dillon; Lewis Zhichang Shi; Sandra Milasta; Robert Carter; David Finkelstein; Laura L McCormick; Patrick Fitzgerald; Hongbo Chi; Joshua Munger; Douglas R Green
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Journal:  Sci Transl Med       Date:  2014-11-19       Impact factor: 17.956

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Journal:  Cell Metab       Date:  2016-09-22       Impact factor: 27.287

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Authors:  Luciana Berod; Christin Friedrich; Amrita Nandan; Jenny Freitag; Stefanie Hagemann; Kirsten Harmrolfs; Aline Sandouk; Christina Hesse; Carla N Castro; Heike Bähre; Sarah K Tschirner; Nataliya Gorinski; Melanie Gohmert; Christian T Mayer; Jochen Huehn; Evgeni Ponimaskin; Wolf-Rainer Abraham; Rolf Müller; Matthias Lochner; Tim Sparwasser
Journal:  Nat Med       Date:  2014-10-05       Impact factor: 53.440

10.  Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.

Authors:  Vicky Lampropoulou; Alexey Sergushichev; Monika Bambouskova; Sharmila Nair; Emma E Vincent; Ekaterina Loginicheva; Luisa Cervantes-Barragan; Xiucui Ma; Stanley Ching-Cheng Huang; Takla Griss; Carla J Weinheimer; Shabaana Khader; Gwendalyn J Randolph; Edward J Pearce; Russell G Jones; Abhinav Diwan; Michael S Diamond; Maxim N Artyomov
Journal:  Cell Metab       Date:  2016-06-30       Impact factor: 27.287
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  107 in total

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Journal:  Cell Mol Immunol       Date:  2019-03-12       Impact factor: 11.530

Review 2.  Macrophage phenotype bioengineered by magnetic, genetic, or pharmacologic interference.

Authors:  Jarek Wosik; Martha Suarez-Villagran; John H Miller; Rafik M Ghobrial; Malgorzata Kloc
Journal:  Immunol Res       Date:  2019-02       Impact factor: 2.829

3.  Probing mitochondrial metabolism in vivo.

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Journal:  Proc Natl Acad Sci U S A       Date:  2018-12-18       Impact factor: 11.205

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Authors:  Liwen Lin; He Xu; Muath Bishawi; FeiFei Feng; Kannan Samy; George Truskey; Andrew S Barbas; Allan D Kirk; Todd V Brennan
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Authors:  Cody A Cunningham; Suzanne Hoppins; Pamela J Fink
Journal:  J Immunol       Date:  2018-08-01       Impact factor: 5.422

7.  Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity.

Authors:  Themis Alissafi; Lydia Kalafati; Maria Lazari; Anastasia Filia; Ismini Kloukina; Maria Manifava; Jong-Hyung Lim; Vasileia Ismini Alexaki; Nicholas T Ktistakis; Triantafyllos Doskas; George A Garinis; Triantafyllos Chavakis; Dimitrios T Boumpas; Panayotis Verginis
Journal:  Cell Metab       Date:  2020-07-31       Impact factor: 27.287

8.  Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target.

Authors:  Changbo Qu; Shaoshi Zhang; Wenshi Wang; Meng Li; Yijin Wang; Marieke van der Heijde-Mulder; Ehsan Shokrollahi; Mohamad S Hakim; Nicolaas J H Raat; Maikel P Peppelenbosch; Qiuwei Pan
Journal:  FASEB J       Date:  2018-08-02       Impact factor: 5.191

9.  An association between mitochondria and microglia effector function. What do we think we know?

Authors:  G Jean Harry; Gabrielle Childers; Sahana Giridharan; Irisyunuel Lopez Hernandes
Journal:  Neuroimmunol Neuroinflamm       Date:  2020-06-16

10.  Mitochondrial DNA Haplogroups and Susceptibility to Neuroblastoma.

Authors:  Xiao Chang; Marina Bakay; Yichuan Liu; Joseph Glessner; Komal S Rathi; Cuiping Hou; Huiqi Qu; Zalman Vaksman; Kenny Nguyen; Patrick M A Sleiman; Sharon J Diskin; John M Maris; Hakon Hakonarson
Journal:  J Natl Cancer Inst       Date:  2020-12-14       Impact factor: 13.506
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