Literature DB >> 28663406

Intercalary allograft augmented with intramedullary cement and plate fixation is a reliable solution after resection of a diaphyseal tumour.

S Gupta1, L A Kafchinski2, K R Gundle3, K Saidi4, A M Griffin5, J S Wunder5, P C Ferguson5.   

Abstract

AIMS: Intercalary allografts following resection of a primary diaphyseal tumour have high rates of complications and failures. At our institution intercalary allografts are augmented with intramedullary cement and fixed using compression plating. Our aim was to evaluate their long-term outcomes. PATIENTS AND METHODS: A total of 46 patients underwent reconstruction with an intercalary allograft between 1989 and 2014. The patients had a mean age of 32.8 years (14 to 77). The most common diagnoses were osteosarcoma (n = 16) and chondrosarcoma (n = 9). The location of the tumours was in the femur in 21, the tibia in 16 and the humerus in nine. Function was assessed using the Musculoskeletal Tumor Society (MSTS) scoring system and the Toronto Extremity Salvage Score (TESS). The survival of the graft and the overall survival were assessed using the Kaplan-Meier method.
RESULTS: The median follow-up was 92 months (4 to 288). The mean MSTS 87 score was 29.1 (19 to 35), the mean MSTS 93 score was 82.2 (50 to 100) and the mean TESS score was 81.2 (43 to 100). Overall survival of the allograft was 84.8%. A total of 15 patients (33%) had a complication. Five allografts were revised for complications and one for local recurrence.
CONCLUSION: Intercalary allografts augmented with intramedullary cement and compression plate fixation provide a reliable and durable method of reconstruction after the excision of a primary diaphyseal bone tumour, with high levels of function and satisfaction. Cite this article: Bone Joint J 2017;99-B:973-8. ©2017 The British Editorial Society of Bone & Joint Surgery.

Entities:  

Keywords:  Cement augmentation; Compression plating; Intercalary allografts

Mesh:

Substances:

Year:  2017        PMID: 28663406     DOI: 10.1302/0301-620X.99B7.BJJ-2016-0996

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  10 in total

1.  Failure rates and functional results for intercalary femur reconstructions after tumour resection.

Authors:  J I Albergo; L C Gaston; G L Farfalli; M Laitinen; M Parry; M A Ayerza; M Risk; L M Jeys; L A Aponte-Tinao
Journal:  Musculoskelet Surg       Date:  2019-03-08

Review 2.  How the Choice of Osteosynthesis Affects the Complication Rate of Intercalary Allograft Reconstruction? A Systematic Review and Meta-analysis.

Authors:  Khodamorad Jamshidi; Mansour Bahardoust; Arman Karimi Behnagh; Abolfazl Bagherifard; Alireza Mirzaei
Journal:  Indian J Orthop       Date:  2021-11-10       Impact factor: 1.251

3.  CORR Insights®: Do Massive Allograft Reconstructions for Tumors of the Femur and Tibia Survive 10 or More Years After Implantation?

Authors:  Kenneth R Gundle
Journal:  Clin Orthop Relat Res       Date:  2020-03       Impact factor: 4.755

4.  CORR Insights®: Does the Addition of a Vascularized Fibula Improve the Results of a Massive Bone Allograft Alone for Intercalary Femur Reconstruction of Malignant Bone Tumors in Children?

Authors:  D Luis Muscolo
Journal:  Clin Orthop Relat Res       Date:  2021-06-01       Impact factor: 4.755

5.  Intercalary Allograft to Reconstruct Large-Segment Diaphysis Defects After Resection of Lower Extremity Malignant Bone Tumor.

Authors:  Qing Liu; Hongbo He; Zhixi Duan; Hao Zeng; Yuhao Yuan; Zhiwei Wang; Wei Luo
Journal:  Cancer Manag Res       Date:  2020-06-08       Impact factor: 3.989

6.  Concave-convex Reaming of Intercalary Allograft: 1-year Clinical Outcomes.

Authors:  Nathan Bastien; Sean Kelly; Dustin Lybeck
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2021-04-20

7.  Application of allograft and absorbable screws in the reconstruction of a massive bone defect following resection of giant osteochondroma: A retrospective study.

Authors:  Zhihao Ma; Qiang Yang; Xinyu Liu; Zhenfeng Li
Journal:  Front Surg       Date:  2022-09-22

Review 8.  Rehabilitation to Improve the Function and Quality of Life of Soft Tissue and Bony Sarcoma Patients.

Authors:  Cody C Andrews; Geoffrey Siegel; Sean Smith
Journal:  Patient Relat Outcome Meas       Date:  2019-12-31

9.  Is three-dimensional-printed custom-made ultra-short stem with a porous structure an acceptable reconstructive alternative in peri-knee metaphysis for the tumorous bone defect?

Authors:  Jie Wang; Jingjing An; Li Min; Chongqi Tu; Minxun Lu; Yuqi Zhang; Jingqi Lin; Yi Luo; Yong Zhou
Journal:  World J Surg Oncol       Date:  2021-08-08       Impact factor: 2.754

10.  Bone defect reconstruction with autologous bone inactivated with liquid nitrogen after resection of primary limb malignant tumors: An observational study.

Authors:  Yuan Li; Yongkun Yang; Zhen Huang; Huachao Shan; Hairong Xu; Xiaohui Niu
Journal:  Medicine (Baltimore)       Date:  2020-06-12       Impact factor: 1.817

  10 in total

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