Literature DB >> 28659641

Lgr5 joins the club of gastric stem cell markers in the corpus.

Toby J Phesse1, Owen J Sansom2.   

Abstract

Several markers of gastric stem cells have been identified in recent years. Now a study demonstrates that Lgr5 marks a population of reserve stem cells located at the base of the corpus glands of the gastric epithelium, and that these cells can also act as a cell-of-origin for gastric tumorigenesis.

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Year:  2017        PMID： 28659641     DOI： 10.1038/ncb3567

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  10 in total

1.  Proliferation and Differentiation of Gastric Mucous Neck and Chief Cells During Homeostasis and Injury-induced Metaplasia.

Authors:  Joseph Burclaff; Spencer G Willet; José B Sáenz; Jason C Mills
Journal:  Gastroenterology       Date:  2019-10-05       Impact factor: 22.682

Review 2.  The cellular origins of cancer with particular reference to the gastrointestinal tract.

Authors:  Malcolm R Alison
Journal:  Int J Exp Pathol       Date:  2020-08-14       Impact factor: 1.925

3.  Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.

Authors:  Seungmin Han; Juergen Fink; David J Jörg; Eunmin Lee; Min Kyu Yum; Lemonia Chatzeli; Sebastian R Merker; Manon Josserand; Teodora Trendafilova; Amanda Andersson-Rolf; Catherine Dabrowska; Hyunki Kim; Ronald Naumann; Ji-Hyun Lee; Nobuo Sasaki; Richard Lester Mort; Onur Basak; Hans Clevers; Daniel E Stange; Anna Philpott; Jong Kyoung Kim; Benjamin D Simons; Bon-Kyoung Koo
Journal:  Cell Stem Cell       Date:  2019-08-15       Impact factor: 24.633

Review 4.  Wnt Signalling in Gastrointestinal Epithelial Stem Cells.

Authors:  Dustin J Flanagan; Chloe R Austin; Elizabeth Vincan; Toby J Phesse
Journal:  Genes (Basel)       Date:  2018-03-23       Impact factor: 4.096

5.  Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori Infection.

Authors:  Koya Suzuki; Kazuhiro Sentani; Hiroo Tanaka; Tomoki Yano; Kazuo Suzuki; Masanobu Oshima; Wataru Yasui; Atsushi Tamura; Sachiko Tsukita
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2019-03-23

6.  SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans.

Authors:  Xuemei Liu; Taolang Li; Zhiyuan Ma; Brigitte Riederer; Dumin Yuan; Jiaxing Zhu; Yunhua Li; Jiaxing An; Guorong Wen; Hai Jin; Xiao Yang; Ursula Seidler; Biguang Tuo
Journal:  Cell Oncol (Dordr)       Date:  2022-04-14       Impact factor: 7.051

7.  Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.

Authors:  Xinye Cui; Tao Qin; Zhengdong Zhao; Guang Yang; Jaceline Gislaine Pires Sanches; Qingqing Zhang; Shujun Fan; Liang Cao; Xiang Hu
Journal:  J Cancer       Date:  2021-06-04       Impact factor: 4.207

Review 8.  Plasticity of differentiated cells in wound repair and tumorigenesis, part I: stomach and pancreas.

Authors:  Joseph Burclaff; Jason C Mills
Journal:  Dis Model Mech       Date:  2018-07-23       Impact factor: 5.758

Review 9.  Targeting Wnt Signaling for the Treatment of Gastric Cancer.

Authors:  Sarah Koushyar; Arfon G Powell; Elizabeth Vincan; Toby J Phesse
Journal:  Int J Mol Sci       Date:  2020-05-30       Impact factor: 5.923

10.  LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial-mesenchymal transition through the Notch1 signaling pathway.

Authors:  Wenxue Liu; Jing Zhang; Xupei Gan; Fangqian Shen; Xiaoming Yang; Na Du; Dandan Xia; Lei Liu; Lianqiao Qiao; Jufang Pan; Yunyan Sun; Xiaowei Xi
Journal:  Cancer Med       Date:  2018-05-18       Impact factor: 4.452
  10 in total

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