Literature DB >> 28658775

Lymphovascular Malformation - A Report of Two Cases.

Mitakshara Sharma1, Varuna Mallya2, Nita Khurana3, Praveen Kumar4, Rajan Duggal5.   

Abstract

Congenital Vascular Malformations (CVM) represents a group of vascular anomalies that are the result of defective development of the vascular system. Lymphatic malformation consists of dilated lymphatic vessels caused by occlusion of the lymphatic drainage system due to congenital malformations or acquired causes such as the effects of trauma, infection, or surgery. Lymphaticovenous Malformation (LVM) is composed of lymphatic and venous channels. The most common sites are the neck and axilla. We report two cases of a four and a half-year-old and a seven-year-old child who presented with complaints of swelling in arm and groin respectively. A provisional diagnosis was made on radiological investigations. Excision was done and the diagnosis was confirmed on histopathology and immunohistochemistry. The cases which were presented as LVMs are rare congenital tumours and require a high index of suspicion on part of pathologist and surgeon to reach a definitive diagnosis.

Entities:  

Keywords:  Congenital tumours; Lymphatics; Podoplanin

Year:  2017        PMID: 28658775      PMCID: PMC5483677          DOI: 10.7860/JCDR/2017/25326.9767

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

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Journal:  Otolaryngol Head Neck Surg       Date:  1999-10       Impact factor: 3.497

3.  Co-expression of VEGF-C and its receptors, VEGFR-2 and VEGFR-3, in endothelial cells of lymphangioma. Implication in autocrine or paracrine regulation of lymphangioma.

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Journal:  Lab Invest       Date:  2001-12       Impact factor: 5.662

4.  Venous thromboembolism and prothrombotic parameters in Klippel-Trenaunay syndrome.

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Journal:  Neth J Med       Date:  2013-06       Impact factor: 1.422

5.  Avian VEGF-C: cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors.

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Journal:  Development       Date:  1998-02       Impact factor: 6.868

6.  Treatment of lymphangiomas with OK-432 (Picibanil) sclerotherapy: a prospective multi-institutional trial.

Authors:  Chantal M Giguère; Nancy M Bauman; Yutaka Sato; Diane K Burke; John H Greinwald; Seth Pransky; Peggy Kelley; Keith Georgeson; Richard J H Smith
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2002-10

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Journal:  Arch Otolaryngol Head Neck Surg       Date:  1995-05

8.  VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development.

Authors:  E Kukk; A Lymboussaki; S Taira; A Kaipainen; M Jeltsch; V Joukov; K Alitalo
Journal:  Development       Date:  1996-12       Impact factor: 6.868

  8 in total
  2 in total

1.  Comprehensive targeted next-generation sequencing in patients with slow-flow vascular malformations.

Authors:  Akifumi Nozawa; Akihiro Fujino; Shunsuke Yuzuriha; Souichi Suenobu; Aiko Kato; Fumiaki Shimizu; Noriko Aramaki-Hattori; Kanako Kuniyeda; Kazuya Sakaguchi; Hidenori Ohnishi; Yoko Aoki; Michio Ozeki
Journal:  J Hum Genet       Date:  2022-09-29       Impact factor: 3.755

2.  Surgical management of bilateral thoracic outlet lymphaticovenous malformations causing recurrent cerebrovascular accidents.

Authors:  Emily Kao; Caitlin Cohan; Emanuel Jaramillo; Jonatthan Jean-Pierre; Arnold Levine; Shahram Aarabi
Journal:  J Vasc Surg Cases Innov Tech       Date:  2022-07-09
  2 in total

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