Literature DB >> 28653153

Application of Benford's law: a valuable tool for detecting scientific papers with fabricated data? : A case study using proven falsified articles against a comparison group.

S Hüllemann1, G Schüpfer2, J Mauch1.   

Abstract

BACKGROUND: In naturally occurring numbers the frequencies of digits 1-9 in the leading position are counterintuitively distributed because the frequencies of occurrence are unequal. Benford-Newcomb's law describes the expected distribution of these frequencies. It was previously shown that known fraudulent articles consistently violated this law.
OBJECTIVE: To compare the features of 12 known fraudulent articles from a single Japanese author to the features of 13 articles in the same research field from other Japanese authors, published during the same time period and identified with a Medline database search.
RESULTS: All 25 articles were assessed to determine whether the data violated the law. Formulas provided by the law were used to determine the frequencies of occurrence for the first two leading digits in manually extracted numbers. It was found that all the known fraudulent papers violated the law and 6 of the 13 articles used for comparison followed the law. Assuming that the articles in the comparison group were not falsified or fabricated, the sensitivity of assessing articles with Benford-Newcomb's law was 100% (95% confidence interval CI: 73.54-100%) but the specificity was only 46.15% (95% CI: 19.22-74.87%) and the positive predictive value was 63.16% (95% CI: 38.36-83.71%).
CONCLUSION: All 12 of the known falsified articles violated Benford-Newcomb's law, which indicated that this analysis had a high sensitivity. The low specificity of the assessment may be explained by the assumptions made about the articles identified for comparison. Violations of Benford-Newcomb's law about the frequencies of the leading digits cannot serve as proof of falsification but they may provide a basis for deeper discussions between the editor and author about a submitted work.

Keywords:  Benford-Newcomb distribution; Data analysis statistical; Fraud; Research misconduct

Mesh:

Substances:

Year:  2017        PMID: 28653153     DOI: 10.1007/s00101-017-0333-1

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  25 in total

1.  Reported data on granisetron and postoperative nausea and vomiting by Fujii et al. Are incredibly nice!

Authors:  P Kranke; C C Apfel; N Roewer; Y Fujii
Journal:  Anesth Analg       Date:  2000-04       Impact factor: 5.108

2.  Scientific fraud in 20 falsified anesthesia papers : detection using financial auditing methods.

Authors:  J Hein; R Zobrist; C Konrad; G Schuepfer
Journal:  Anaesthesist       Date:  2012-06       Impact factor: 1.041

3.  Probability screening in manuscripts submitted to biomedical journals--an effective tool or a statistical quagmire?

Authors:  D R Miller
Journal:  Anaesthesia       Date:  2015-05-29       Impact factor: 6.955

4.  Research integrity-have we made progress?

Authors: 
Journal:  Lancet       Date:  2017-05-04       Impact factor: 79.321

5.  Clonidine-ephedrine combination reduces pain on injection of propofol and blunts hemodynamic stress responses during the induction sequence.

Authors:  Tadahiko Ishiyama; Satoshi Kashimoto; Takeshi Oguchi; Atsushi Furuya; Hisashi Fukushima; Teruo Kumazawa
Journal:  J Clin Anesth       Date:  2006-05       Impact factor: 9.452

6.  Pretreatment with topical 60% lidocaine tape reduces pain on injection of propofol.

Authors:  S Yokota; T Komatsu; Y Komura; K Nishiwaki; T Kimura; R Hosoda; Y Shimada
Journal:  Anesth Analg       Date:  1997-09       Impact factor: 5.108

7.  Orally administered clonidine significantly reduces pain during injection of propofol.

Authors:  T Yoshikawa; Z Wajima; A Ogura; T Inoue; R Ogawa
Journal:  Br J Anaesth       Date:  2001-06       Impact factor: 9.166

8.  How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen.

Authors:  Tomoki Nishiyama
Journal:  J Anesth       Date:  2005       Impact factor: 2.078

9.  Propofol injection pain is not alleviated by pretreatment with flurbiprofen axetil, a prodrug of a nonsteroidal antiinflammatory drug.

Authors:  F Karasawa; T Ehata; T Okuda; T Satoh
Journal:  J Anesth       Date:  2000       Impact factor: 2.078

10.  Evaluation of low-dose propofol preadministration to attenuate vascular pain during induction of anesthesia.

Authors:  Mitsuharu Kodaka; Shin-Ichiro Okuyama; Akihiko Maeyama; Kaoru Koyama; Hideki Miyao
Journal:  J Clin Anesth       Date:  2007-09       Impact factor: 9.452

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  1 in total

1.  Pinocchio testing in the forensic analysis of waiting lists: using public waiting list data from Finland and Spain for testing Newcomb-Benford's Law.

Authors:  Jaime Pinilla; Beatriz G López-Valcárcel; Christian González-Martel; Salvador Peiro
Journal:  BMJ Open       Date:  2018-05-09       Impact factor: 2.692

  1 in total

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