Bei Chang1, Neelam Ahuja1, Chi Ma1, Xiaohua Liu1. 1. Department of Biomedical Sciences, Texas A&M University College of Dentistry, Dallas, TX 75246, USA.
Abstract
Injectable scaffolds are appealing for tissue regeneration because they offer many advantages over pre-formed scaffolds. This article provides a comprehensive review of the injectable scaffolds currently being investigated for dental and craniofacial tissue regeneration. First, we provide an overview of injectable scaffolding materials, including natural, synthetic, and composite biomaterials. Next, we discuss a variety of characteristic parameters and gelation mechanisms of the injectable scaffolds. The advanced injectable scaffolding systems developed in recent years are then illustrated. Furthermore, we summarize the applications of the injectable scaffolds for the regeneration of dental and craniofacial tissues that include pulp, dentin, periodontal ligament, temporomandibular joint, and alveolar bone. Finally, our perspectives on the injectable scaffolds for dental and craniofacial tissue regeneration are offered as signposts for the future advancement of this field.
Injectable scaffolds are appealing for tissue regeneration because they offer many advantages over pre-formed scaffolds. This article provides a comprehensive review of the injectable scaffolds currently being investigated for dental and pan class="Disease">craniofacial tissue regeneration. First, we provide an overview of injectable scaffolding materials, including natural, synthetic, and composite biomaterials. Next, we discuss a variety of characteristic parameters and gelation mechanisms of the injectable scaffolds. The advanced injectable scaffolding systems developed in recent years are then illustrated. Furthermore, we summarize the applications of the injectable scaffolds for the regeneration of dental and craniofacial tissues that include pulp, dentin, periodontal ligament, temporomandibular joint, and alveolar bone. Finally, our perspectives on the injectable scaffolds for dental and craniofacial tissue regeneration are offered as signposts for the future advancement of this field.
Authors: Eric Hesse; Theresa E Hefferan; James E Tarara; Carl Haasper; Rupert Meller; Christian Krettek; Lichun Lu; Michael J Yaszemski Journal: J Biomed Mater Res A Date: 2010-08 Impact factor: 4.396
Authors: Ramkumar T Annamalai; Xiaowei Hong; Nicholas G Schott; Gopinath Tiruchinapally; Benjamin Levi; Jan P Stegemann Journal: Biomaterials Date: 2019-04-04 Impact factor: 12.479