Literature DB >> 28643752

Dosimetric characterization of optically stimulated luminescence dosimeter with therapeutic photon beams for use in clinical radiotherapy measurements.

Retna Ponmalar1, Ravikumar Manickam2, K M Ganesh2, Sathiyan Saminathan2, Arun Raman2, Henry Finlay Godson1.   

Abstract

AIM: The modern radiotherapy techniques impose new challenges for dosimetry systems with high precision and accuracy in in vivo and in phantom dosimetric measurements. The knowledge of the basic characterization of a dosimetric system before patient dose verification is crucial. This incites the investigation of the potential use of nanoDot optically stimulated luminescence dosimeter (OSLD) for application in radiotherapy with therapeutic photon beams.
MATERIALS AND METHODS: Measurements were carried out with nanoDot OSLDs to evaluate the dosimetric characteristics such as dose linearity, dependency on field size, dose rate, energy and source-to-surface distance (SSD), reproducibility, fading effect, reader stability, and signal depletion per read out with cobalt-60 (60 Co) beam, 6 and 18 MV therapeutic photon beams. The data acquired with OSLDs were validated with ionization chamber data where applicable.
RESULTS: Good dose linearity was observed for doses up to 300 cGy and above which supralinear behavior. The standard uncertainty with field size observed was 1.10% ± 0.4%, 1.09% ± 0.34%, and 1.2% ± 0.26% for 6 MV, 18 MV, and 60 Co beam, respectively. The maximum difference with dose rate was 1.3% ± 0.4% for 6 MV and 1.4% ± 0.4% for 18 MV photon beams. The largest variation in SSD was 1.5% ± 1.2% for 60 Co, 1.5% ± 0.9% for 6 MV, and 1.5% ± 1.3% for 18 MV photon beams. The energy dependence of OSL response at 18 MV and 60 Co with 6 MV beam was 1.5% ± 0.7% and 1.7% ± 0.6%, respectively. In addition, good reproducibility, stability after the decay of transient signal, and predictable fading were observed.
CONCLUSION: The results obtained in this study indicate the efficacy and suitability of nanoDot OSLD for dosimetric measurements in clinical radiotherapy.

Entities:  

Mesh:

Year:  2017        PMID: 28643752     DOI: 10.4103/0973-1482.199432

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN: 1998-4138            Impact factor:   1.805


  1 in total

1.  A strategy to determine off-axis dosimetric leaf gap using OSLD and EPID.

Authors:  Janahiraman Divyalakshmi; K Mohamathu Rafic; Ebenezer Suman Babu; Timothy Peace Balasingh; Amalan Sebastin; Christopher J Sujith; L Jose Solomon Raj
Journal:  Rep Pract Oncol Radiother       Date:  2021-12-30
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.