Literature DB >> 2863599

Isolation of AIDS-associated retroviruses from cerebrospinal fluid and brain of patients with neurological symptoms.

J A Levy, J Shimabukuro, H Hollander, J Mills, L Kaminsky.   

Abstract

Acquired-immunodeficiency-syndrome (AIDS)-associated retroviruses (ARV) have been isolated from the cerebrospinal fluid and brain of homosexual men presenting with neurological symptoms. Most of these patients also met the clinical criteria for AIDS. The viruses grew readily in peripheral mononuclear cells and were identified by their induction of cytopathic effects and ARV antigens in culture. The results suggest that ARV could be the cause of the neurological syndromes in AIDS patients and indicate that the virus can infect cells other than T lymphocytes.

Entities:  

Keywords:  Acquired Immunodeficiency Syndrome; Americas; Behavior; Biology; Central Nervous System; Central Nervous System Effects; Developed Countries; Developing Countries; Diseases; Examinations And Diagnoses; Hiv Infections; Homosexuals; Laboratory Examinations And Diagnoses; Neurologic Effects; North America; Northern America; Physiology; Sex Behavior; United States; Viral Diseases

Mesh:

Substances:

Year:  1985        PMID: 2863599

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  75 in total

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Journal:  J Neurol       Date:  2011-09-20       Impact factor: 4.849

2.  Sequence homology between HIV gp120, rabies virus glycoprotein, and snake venom neurotoxins. Is the nicotinic acetylcholine receptor an HIV receptor?

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Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

3.  Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus.

Authors:  C Cheng-Mayer; C Weiss; D Seto; J A Levy
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

4.  AIDS virus and the brain.

Authors:  L R Sharer
Journal:  West J Med       Date:  1987-01

5.  Neurological manifestations of human immunodeficiency virus infection.

Authors:  C A Carne; M W Adler
Journal:  Br Med J (Clin Res Ed)       Date:  1986-08-23

6.  Dementia and ataxia in a patient with AIDS.

Authors:  G L Clark; H V Vinters
Journal:  West J Med       Date:  1987-01

7.  Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry.

Authors:  K Mori; D J Ringler; R C Desrosiers
Journal:  J Virol       Date:  1993-05       Impact factor: 5.103

8.  Analysis of circulating immune complexes from patients with ankylosing spondylitis by gel electrophoresis and immunoblotting using antiserum against a psoriasis associated retrovirus-like particle.

Authors:  E Rødahl; O J Iversen
Journal:  Ann Rheum Dis       Date:  1986-11       Impact factor: 19.103

9.  Neuropathology of acquired immune deficiency syndrome (AIDS) in 53 autopsy cases with particular emphasis on microglial nodules and multinucleated giant cells.

Authors:  T Kato; A Hirano; J F Llena; H M Dembitzer
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

10.  Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism.

Authors:  A V Moses; F E Bloom; C D Pauza; J A Nelson
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-15       Impact factor: 11.205

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