Takeshi Morii1, Tomonori Kishino2, Naoko Shimamori2, Mitsue Motohashi2, Hiroaki Ohnishi2, Keita Honya3, Takayuki Aoyagi4, Takashi Tajima4, Shoichi Ichimura4. 1. Department of Orthopaedic Surgery, Faculty of Medicine, Kyorin University, 6-20-2 Shinkawa, Mitaka, Tokyo, 161-8611, Japan. t-morii@gb3.so-net.ne.jp. 2. Department of Laboratory Medicine, Faculty of Medicine, Kyorin University, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan. 3. Department of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, 5-4-1 Shimorenjaku, Mitaka, Tokyo, 181-8612, Japan. 4. Department of Orthopaedic Surgery, Faculty of Medicine, Kyorin University, 6-20-2 Shinkawa, Mitaka, Tokyo, 161-8611, Japan.
Abstract
PURPOSE: Preoperative discrimination between benign and malignant soft tissue tumors is critical for the prevention of excess application of magnetic resonance imaging and biopsy as well as unplanned resection. Although ultrasound, including power Doppler imaging, is an easy, noninvasive, and cost-effective modality for screening soft tissue tumors, few studies have investigated reliable discrimination between benign and malignant soft tissue tumors. METHODS: To establish a modality for discrimination between benign and malignant soft tissue tumors using ultrasound, we extracted the significant risk factors for malignancy based on ultrasound information from 40 malignant and 56 benign pathologically diagnosed soft tissue tumors and established a scoring system based on these risk factors. RESULTS: The maximum size, tumor margin, and vascularity evaluated using ultrasound were extracted as significant risk factors. Using the odds ratio from a multivariate regression model, a scoring system was established. Receiver operating characteristic analyses revealed a high area under the curve value (0.85), confirming the accuracy of the scoring system. CONCLUSION: Ultrasound is a useful modality for establishing the differential diagnosis between benign and malignant soft tissue tumors.
PURPOSE: Preoperative discrimination between benign and malignant soft tissue tumors is critical for the prevention of excess application of magnetic resonance imaging and biopsy as well as unplanned resection. Although ultrasound, including power Doppler imaging, is an easy, noninvasive, and cost-effective modality for screening soft tissue tumors, few studies have investigated reliable discrimination between benign and malignant soft tissue tumors. METHODS: To establish a modality for discrimination between benign and malignant soft tissue tumors using ultrasound, we extracted the significant risk factors for malignancy based on ultrasound information from 40 malignant and 56 benign pathologically diagnosed soft tissue tumors and established a scoring system based on these risk factors. RESULTS: The maximum size, tumor margin, and vascularity evaluated using ultrasound were extracted as significant risk factors. Using the odds ratio from a multivariate regression model, a scoring system was established. Receiver operating characteristic analyses revealed a high area under the curve value (0.85), confirming the accuracy of the scoring system. CONCLUSION: Ultrasound is a useful modality for establishing the differential diagnosis between benign and malignant soft tissue tumors.
Authors: Gerd Bodner; Michael F H Schocke; Franz Rachbauer; Klaus Seppi; Siegfried Peer; Anke Fierlinger; Tarek Sununu; Werner R Jaschke Journal: Radiology Date: 2002-05 Impact factor: 11.105
Authors: Esther H Y Hung; James F Griffith; Stefanie W Y Yip; Marina Ivory; Jeremiah C H Lee; Alex W H Ng; Cina S L Tong Journal: Skeletal Radiol Date: 2020-01-03 Impact factor: 2.199