Literature DB >> 28616696

[Epileptic seizures and epilepsy after a stroke : Incidence, prevention and treatment].

F Benninger1, M Holtkamp2.   

Abstract

Following stroke, 3-6% of patients develop acute symptomatic seizures within the first 7 days. The rate is higher after cerebral haemorrhage compared to ischaemia. In 10-12% of patients, after more than 7 days unprovoked seizures occur. Due to these low incidence rates, primary prophylaxis with antiepileptic drugs is generally not necessary. Following one acute symptomatic seizure, recurrence risk within the first 7 days post-stroke is 10-20%, generally arguing against secondary prophylaxis with an antiepileptic drug. In clinical practice however, antiepileptic drug treatment in this constellation is often initiated. If this is done, the antiepileptic drug should be withdrawn soon after the acute phase, as the long-term risk for manifestation of an unprovoked seizure is approximately 30%. Following one post-stroke unprovoked seizure, recurrence risk within the next 10 years is more than 70%, this defines epilepsy. In this case, antiepileptic drug treatment is regularly recommended.

Entities:  

Keywords:  Acute symptomatic seizure; Antiepileptic drug treatment; Primary prophylaxis; Secondary prophylaxis; Unprovoked seizure

Mesh:

Substances:

Year:  2017        PMID: 28616696     DOI: 10.1007/s00115-017-0358-3

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  41 in total

Review 1.  Pathobiology of ischaemic stroke: an integrated view.

Authors:  U Dirnagl; C Iadecola; M A Moskowitz
Journal:  Trends Neurosci       Date:  1999-09       Impact factor: 13.837

2.  Are post intracerebral hemorrhage seizures prevented by anti-epileptic treatment?

Authors:  Ronit Gilad; Mona Boaz; Ron Dabby; Menachem Sadeh; Yair Lampl
Journal:  Epilepsy Res       Date:  2011-05-31       Impact factor: 3.045

Review 3.  Emergency EEG and continuous EEG monitoring in acute ischemic stroke.

Authors:  Kenneth G Jordan
Journal:  J Clin Neurophysiol       Date:  2004 Sep-Oct       Impact factor: 2.177

4.  Randomised study of antiepileptic drug withdrawal in patients in remission. Medical Research Council Antiepileptic Drug Withdrawal Study Group.

Authors: 
Journal:  Lancet       Date:  1991-05-18       Impact factor: 79.321

Review 5.  Initial treatment of epilepsy: special issues in treating the elderly.

Authors:  Gregory K Bergey
Journal:  Neurology       Date:  2004-11-23       Impact factor: 9.910

6.  Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors.

Authors:  R Roivainen; E Haapaniemi; J Putaala; M Kaste; T Tatlisumak
Journal:  Eur J Neurol       Date:  2013-04-14       Impact factor: 6.089

7.  Long-term outcome of cerebral infarction in young adults.

Authors:  H Naess; H I Nyland; L Thomassen; J Aarseth; K-M Myhr
Journal:  Acta Neurol Scand       Date:  2004-08       Impact factor: 3.209

8.  Are Early Seizures Predictive of Epilepsy after a Stroke? Results of a Population-Based Study.

Authors:  Anna Serafini; Gian Luigi Gigli; Giorgia Gregoraci; Francesco Janes; Iacopo Cancelli; Stefano Novello; Mariarosaria Valente
Journal:  Neuroepidemiology       Date:  2015-07-28       Impact factor: 3.282

9.  Risk of unprovoked seizure after acute symptomatic seizure: effect of status epilepticus.

Authors:  D C Hesdorffer; G Logroscino; G Cascino; J F Annegers; W A Hauser
Journal:  Ann Neurol       Date:  1998-12       Impact factor: 10.422

10.  Impact of seizures on morbidity and mortality after stroke: a Canadian multi-centre cohort study.

Authors:  J G Burneo; J Fang; G Saposnik
Journal:  Eur J Neurol       Date:  2009-07-21       Impact factor: 6.089

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  2 in total

1.  Electroencephalographic features in pediatric patients with moyamoya disease in China.

Authors:  Jia Lu; Qing Xia; Tuanfeng Yang; Jun Qiang; Xianzeng Liu; Xun Ye; Rong Wang
Journal:  Chin Neurosurg J       Date:  2020-01-13

Review 2.  Seizures and Epilepsy After Stroke: Epidemiology, Biomarkers and Management.

Authors:  Marian Galovic; Carolina Ferreira-Atuesta; Laura Abraira; Nico Döhler; Lucia Sinka; Francesco Brigo; Carla Bentes; Johan Zelano; Matthias J Koepp
Journal:  Drugs Aging       Date:  2021-02-23       Impact factor: 3.923

  2 in total

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