OBJECTIVES: We analysed the long-term outcome of 232 young adults aged 15-49 years with first-ever cerebral infarction in 1988-1997 in western Norway. MATERIAL AND METHODS: Mortality, recurrence, epilepsy, functional state as evaluated by modified Rankin scale (mRS), and employment were analysed at follow-up (mean time 5.7 years). RESULTS: Twenty-three (9.9%) patients had died. Recurrence occurred in 9.9%, and post-stroke seizures developed in 10.5%. Recurrence was associated with diabetes mellitus (P = 0.005). Favourable functional outcome (mRS = 2) was found in 77.9%. The functional outcome was better in posterior than anterior circulation infarctions (P = 0.011). Unfavourable functional outcome (mRS > 2) was associated with diabetes mellitus (P = 0.001) and severity of neurological deficits on admission for the index stroke (P < 0.001). Only 58.3% were employed at follow-up. CONCLUSION: This population-based study shows that, although the majority had favourable functional outcome, cerebral infarction had major long-term impact on young adults as evaluated by mortality, recurrence and employment status.
OBJECTIVES: We analysed the long-term outcome of 232 young adults aged 15-49 years with first-ever cerebral infarction in 1988-1997 in western Norway. MATERIAL AND METHODS: Mortality, recurrence, epilepsy, functional state as evaluated by modified Rankin scale (mRS), and employment were analysed at follow-up (mean time 5.7 years). RESULTS: Twenty-three (9.9%) patients had died. Recurrence occurred in 9.9%, and post-stroke seizures developed in 10.5%. Recurrence was associated with diabetes mellitus (P = 0.005). Favourable functional outcome (mRS = 2) was found in 77.9%. The functional outcome was better in posterior than anterior circulation infarctions (P = 0.011). Unfavourable functional outcome (mRS > 2) was associated with diabetes mellitus (P = 0.001) and severity of neurological deficits on admission for the index stroke (P < 0.001). Only 58.3% were employed at follow-up. CONCLUSION: This population-based study shows that, although the majority had favourable functional outcome, cerebral infarction had major long-term impact on young adults as evaluated by mortality, recurrence and employment status.
Authors: J Mocco; David A Wilson; Ricardo J Komotar; Joseph Zurica; William J Mack; Hadi J Halazun; Raheleh Hatami; Robert R Sciacca; E Sander Connolly; Eric J Heyer Journal: Neurosurgery Date: 2006-05 Impact factor: 4.654
Authors: Aneesh B Singhal; José Biller; Mitchell S Elkind; Heather J Fullerton; Edward C Jauch; Steven J Kittner; Deborah A Levine; Steven R Levine Journal: Neurology Date: 2013-08-14 Impact factor: 9.910
Authors: Noortje A M M Maaijwee; Loes C A Rutten-Jacobs; Pauline Schaapsmeerders; Ewoud J van Dijk; Frank-Erik de Leeuw Journal: Nat Rev Neurol Date: 2014-04-29 Impact factor: 42.937
Authors: Renate M Arntz; Mayte E van Alebeek; Nathalie E Synhaeve; Jeske van Pamelen; Noortje Amm Maaijwee; Hennie Schoonderwaldt; Maureen J van der Vlugt; Ewoud J van Dijk; Loes Ca Rutten-Jacobs; Frank-Erik de Leeuw Journal: Eur Stroke J Date: 2016-10-14
Authors: L Tancredi; F Martinelli Boneschi; M Braga; I Santilli; C Scaccabarozzi; P Lattuada; M Sessa; L Fumagalli; S Iurlaro; I Neromante; M L De Lodovici; D V Roccatagliata; G Giacalone; M Arnaboldi; V Crespi; E Agostoni; G C Comi; C Ferrarese; R Sterzi Journal: Stroke Res Treat Date: 2013-02-26