Literature DB >> 28611479

NAFLD: PNPLA3 and obesity: a synergistic relationship in NAFLD.

Jake P Mann1, Quentin M Anstee2.   

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Year:  2017        PMID: 28611479     DOI: 10.1038/nrgastro.2017.74

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN: 1759-5045            Impact factor:   46.802


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  10 in total

1.  The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells.

Authors:  Francesca Virginia Bruschi; Thierry Claudel; Matteo Tardelli; Alessandra Caligiuri; Thomas M Stulnig; Fabio Marra; Michael Trauner
Journal:  Hepatology       Date:  2017-04-18       Impact factor: 17.425

2.  Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma.

Authors:  Y-L Liu; G L Patman; J B S Leathart; A-C Piguet; A D Burt; J-F Dufour; C P Day; A K Daly; H L Reeves; Q M Anstee
Journal:  J Hepatol       Date:  2014-03-06       Impact factor: 25.083

Review 3.  The Genetics of Nonalcoholic Fatty Liver Disease: Spotlight on PNPLA3 and TM6SF2.

Authors:  Quentin M Anstee; Christopher P Day
Journal:  Semin Liver Dis       Date:  2015-09-17       Impact factor: 6.115

4.  PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease.

Authors:  Jiayun Shen; Grace Lai-Hung Wong; Henry Lik-Yuen Chan; Ruth Suk-Mei Chan; Hoi-Yun Chan; Winnie Chiu-Wing Chu; Bernice Ho-Ki Cheung; David Ka-Wai Yeung; Liz Sin Li; Mandy Man-Mei Sea; Jean Woo; Vincent Wai-Sun Wong
Journal:  J Gastroenterol Hepatol       Date:  2015-01       Impact factor: 4.029

5.  Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

Authors:  Luca Valenti; Ahmad Al-Serri; Ann K Daly; Enrico Galmozzi; Raffaela Rametta; Paola Dongiovanni; Valerio Nobili; Enrico Mozzi; Giancarlo Roviaro; Ester Vanni; Elisabetta Bugianesi; Marco Maggioni; Anna Ludovica Fracanzani; Silvia Fargion; Christopher P Day
Journal:  Hepatology       Date:  2010-04       Impact factor: 17.425

6.  The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.

Authors:  Rosellina Margherita Mancina; Paola Dongiovanni; Salvatore Petta; Piero Pingitore; Marica Meroni; Raffaela Rametta; Jan Borén; Tiziana Montalcini; Arturo Pujia; Olov Wiklund; George Hindy; Rocco Spagnuolo; Benedetta Maria Motta; Rosaria Maria Pipitone; Antonio Craxì; Silvia Fargion; Valerio Nobili; Pirjo Käkelä; Vesa Kärjä; Ville Männistö; Jussi Pihlajamäki; Dermot F Reilly; Jose Castro-Perez; Julia Kozlitina; Luca Valenti; Stefano Romeo
Journal:  Gastroenterology       Date:  2016-02-02       Impact factor: 22.682

Review 7.  The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes.

Authors:  Rachel J Perry; Varman T Samuel; Kitt F Petersen; Gerald I Shulman
Journal:  Nature       Date:  2014-06-05       Impact factor: 49.962

8.  Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

Authors:  Luca A Lotta; Pawan Gulati; Felix R Day; Felicity Payne; Halit Ongen; Martijn van de Bunt; Kyle J Gaulton; John D Eicher; Stephen J Sharp; Jian'an Luan; Emanuella De Lucia Rolfe; Isobel D Stewart; Eleanor Wheeler; Sara M Willems; Claire Adams; Hanieh Yaghootkar; Nita G Forouhi; Kay-Tee Khaw; Andrew D Johnson; Robert K Semple; Timothy Frayling; John R B Perry; Emmanouil Dermitzakis; Mark I McCarthy; Inês Barroso; Nicholas J Wareham; David B Savage; Claudia Langenberg; Stephen O'Rahilly; Robert A Scott
Journal:  Nat Genet       Date:  2016-11-14       Impact factor: 38.330

9.  TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.

Authors:  Yang-Lin Liu; Helen L Reeves; Alastair D Burt; Dina Tiniakos; Stuart McPherson; Julian B S Leathart; Michael E D Allison; Graeme J Alexander; Anne-Christine Piguet; Rodolphe Anty; Peter Donaldson; Guruprasad P Aithal; Sven Francque; Luc Van Gaal; Karine Clement; Vlad Ratziu; Jean-Francois Dufour; Christopher P Day; Ann K Daly; Quentin M Anstee
Journal:  Nat Commun       Date:  2014-06-30       Impact factor: 14.919

10.  Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci.

Authors:  Stefan Stender; Julia Kozlitina; Børge G Nordestgaard; Anne Tybjærg-Hansen; Helen H Hobbs; Jonathan C Cohen
Journal:  Nat Genet       Date:  2017-04-24       Impact factor: 38.330

  10 in total
  7 in total

1.  Voluntary exercise in mice fed an obesogenic diet alters the hepatic immune phenotype and improves metabolic parameters - an animal model of life style intervention in NAFLD.

Authors:  Nadine Gehrke; Jana Biedenbach; Yvonne Huber; Beate K Straub; Peter R Galle; Perikles Simon; Jörn M Schattenberg
Journal:  Sci Rep       Date:  2019-03-08       Impact factor: 4.379

Review 2.  Evolving Role for Pharmacotherapy in NAFLD/NASH.

Authors:  Suzanna L Attia; Samir Softic; Marialena Mouzaki
Journal:  Clin Transl Sci       Date:  2020-08-25       Impact factor: 4.689

3.  Obesity Risk Assessment Tool for Low-Income Spanish Speaking Immigrant Parents with Young Children: Validity with BMI and Biomarkers of Obesity.

Authors:  Marilyn S Townsend; Mical K Shilts; Louise Lanoue; Christiana Drake; L Karina Díaz Rios; Dennis M Styne; Nancy L Keim; Lenna Ontai
Journal:  Nutrients       Date:  2020-11-22       Impact factor: 5.717

4.  Single Nucleotide Polymorphism of Genes Associated with Metabolic Fatty Liver Disease.

Authors:  Tong Mu; Linrui Peng; Xinglei Xie; He He; Qing Shao; Xiran Wang; Yuwei Zhang
Journal:  J Oncol       Date:  2022-02-03       Impact factor: 4.375

5.  PNPLA3 rs738409 Polymorphism Predicts Development and Severity of Hepatic Steatosis but Not Metabolic Syndrome in Celiac Disease.

Authors:  Raffaella Tortora; Antonio Rispo; Anna Alisi; Nicola Imperatore; Annalisa Crudele; Francesca Ferretti; Valerio Nobili; Luca Miele; Nicolò Gerbino; Nicola Caporaso; Filomena Morisco
Journal:  Nutrients       Date:  2018-09-05       Impact factor: 5.717

6.  PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells.

Authors:  Francesca Virginia Bruschi; Thierry Claudel; Matteo Tardelli; Patrick Starlinger; Fabio Marra; Michael Trauner
Journal:  Hepatol Commun       Date:  2019-07-15

7.  Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals.

Authors:  Chuan Gao; Anthony Marcketta; Joshua D Backman; Colm O'Dushlaine; Jeffrey Staples; Manuel Allen Revez Ferreira; Luca A Lotta; John D Overton; Jeffrey G Reid; Tooraj Mirshahi; Aris Baras; Gonçalo Abecasis; Alan R Shuldiner; Cristopher V Van Hout; Shane McCarthy
Journal:  Genet Epidemiol       Date:  2021-06-29       Impact factor: 2.344

  7 in total

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