Literature DB >> 28606953

Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease.

Cynthia R Clark1, Meghan A Bowler1, J Caleb Snider1, W David Merryman2.   

Abstract

Entities:  

Keywords:  aortic valve; aortic valve, calcification of; cadherins; calcification, physiologic

Mesh：

Substances：

Year:  2017        PMID： 28606953      PMCID： PMC5523848          DOI： 10.1161/CIRCULATIONAHA.117.027771

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  5 in total

1.  Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts.

Authors:  Joshua D Hutcheson; Joseph Chen; M K Sewell-Loftin; Larisa M Ryzhova; Charles I Fisher; Yan Ru Su; W David Merryman
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-11-15       Impact factor: 8.311

2.  Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction.

Authors:  Joseph Chen; Larisa M Ryzhova; M K Sewell-Loftin; Christopher B Brown; Stacey S Huppert; H Scott Baldwin; W David Merryman
Journal:  Arterioscler Thromb Vasc Biol       Date:  2015-05-28       Impact factor: 8.311

3.  Altered DNA Methylation of Long Noncoding RNA H19 in Calcific Aortic Valve Disease Promotes Mineralization by Silencing NOTCH1.

Authors:  Fayez Hadji; Marie-Chloé Boulanger; Simon-Pierre Guay; Nathalie Gaudreault; Soumiya Amellah; Guada Mkannez; Rihab Bouchareb; Joël Tremblay Marchand; Mohamed Jalloul Nsaibia; Sandra Guauque-Olarte; Philippe Pibarot; Luigi Bouchard; Yohan Bossé; Patrick Mathieu
Journal:  Circulation       Date:  2016-10-27       Impact factor: 29.690

4.  Lnc-ing NOTCH1 to Idiopathic Calcific Aortic Valve Disease.

Authors:  W David Merryman; Cynthia R Clark
Journal:  Circulation       Date:  2016-10-27       Impact factor: 29.690

5.  Mutations in NOTCH1 cause aortic valve disease.

Authors:  Vidu Garg; Alecia N Muth; Joshua F Ransom; Marie K Schluterman; Robert Barnes; Isabelle N King; Paul D Grossfeld; Deepak Srivastava
Journal:  Nature       Date:  2005-07-17       Impact factor: 49.962
  5 in total
  22 in total

Review 1.  Valvular disease: Cadherin 11 in calcific aortic valve disease.

Authors:  Karina Huynh
Journal:  Nat Rev Cardiol       Date:  2017-06-29       Impact factor: 32.419

2.  Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease.

Authors:  Christina V Theodoris; Ping Zhou; Lei Liu; Yu Zhang; Tomohiro Nishino; Yu Huang; Aleksandra Kostina; Sanjeev S Ranade; Casey A Gifford; Vladimir Uspenskiy; Anna Malashicheva; Sheng Ding; Deepak Srivastava
Journal:  Science       Date:  2020-12-10       Impact factor: 47.728

3.  Rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification.

Authors:  Kiran A Vaidya; Matthew P Donnelly; Ablajan Mahmut; Jae Woong Jang; Terence W Gee; Marine-Ayan Ibrahim Aibo; Robert Bossong; Clare Hall; Sanjay Samb; Jonathan Chen; Jonathan T Butcher
Journal:  Cardiovasc Pathol       Date:  2022-01-21       Impact factor: 2.185

4.  Macrophages Promote Aortic Valve Cell Calcification and Alter STAT3 Splicing.

Authors:  Michael A Raddatz; Tessa Huffstater; Matthew R Bersi; Bradley I Reinfeld; Matthew Z Madden; Sabrina E Booton; W Kimryn Rathmell; Jeffrey C Rathmell; Brian R Lindman; Meena S Madhur; W David Merryman
Journal:  Arterioscler Thromb Vasc Biol       Date:  2020-04-16       Impact factor: 8.311

Review 5.  Adaptive immune cells in calcific aortic valve disease.

Authors:  Michael A Raddatz; Meena S Madhur; W David Merryman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-05-03       Impact factor: 4.733

6.  Cadherin-11 as a regulator of valve myofibroblast mechanobiology.

Authors:  Meghan A Bowler; Matthew R Bersi; Larisa M Ryzhova; Rachel J Jerrell; Aron Parekh; W David Merryman
Journal:  Am J Physiol Heart Circ Physiol       Date:  2018-10-25       Impact factor: 4.733

7.  Non-destructive two-photon excited fluorescence imaging identifies early nodules in calcific aortic-valve disease.

Authors:  Lauren M Baugh; Zhiyi Liu; Kyle P Quinn; Sam Osseiran; Conor L Evans; Gordon S Huggins; Philip W Hinds; Lauren D Black; Irene Georgakoudi
Journal:  Nat Biomed Eng       Date:  2017-11-06       Impact factor: 25.671

8.  Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction.

Authors:  Alison K Schroer; Matthew R Bersi; Cynthia R Clark; Qinkun Zhang; Lehanna H Sanders; Antonis K Hatzopoulos; Thomas L Force; Susan M Majka; Hind Lal; W David Merryman
Journal:  JCI Insight       Date:  2019-09-19

9.  Side-specific valvular endothelial-interstitial cell mechano-communication via cadherin-11.

Authors:  Camryn L Johnson; W David Merryman
Journal:  J Biomech       Date:  2021-02-10       Impact factor: 2.712

Review 10.  Dissecting Calcific Aortic Valve Disease-The Role, Etiology, and Drivers of Valvular Fibrosis.

Authors:  Petra Büttner; Lukas Feistner; Philipp Lurz; Holger Thiele; Joshua D Hutcheson; Florian Schlotter
Journal:  Front Cardiovasc Med       Date:  2021-05-10
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