Literature DB >> 2860210

Putative amino acid transmitters in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer's dementia.

C C Smith, D M Bowen, P T Francis, J S Snowden, D Neary.   

Abstract

Concentrations of individual free amino acids were determined in lumbar cerebrospinal fluid (CSF) from patients with various complaints including histologically verified Alzheimer's dementia. Glycine and glutamine in the CSF of Alzheimer's dementia samples were lower than that of control samples. Only the concentration of glutamic acid in Alzheimer's dementia patients correlated with psychological measures. The reduction in glycine concentration was not specific for Alzheimer's dementia.

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Year:  1985        PMID： 2860210      PMCID： PMC1028335          DOI： 10.1136/jnnp.48.5.469

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  11 in total

1.  The token test: A sensitive test to detect receptive disturbances in aphasics.

Authors:  E DE RENZI; L A VIGNOLO
Journal:  Brain       Date:  1962-12       Impact factor: 13.501

2.  Studies of the inter-relationship between cerebrospinal fluid and plasma amino acid concentrations in normal individuals.

Authors:  E H McGale; I F Pye; C Stonier; E C Hutchinson; G M Aber
Journal:  J Neurochem       Date:  1977-08       Impact factor: 5.372

3.  The biochemistry of memory: a new and specific hypothesis.

Authors:  G Lynch; M Baudry
Journal:  Science       Date:  1984-06-08       Impact factor: 47.728

4.  Effects of albumin, amino acids, and clofibrate on the uptake of tryptophan by the rat brain.

Authors:  D L Bloxam; M D Tricklebank; A J Patel; G Curzon
Journal:  J Neurochem       Date:  1980-01       Impact factor: 5.372

5.  Dementia in epilepsy.

Authors:  M R Trimble
Journal:  Acta Neurol Scand Suppl       Date:  1984

6.  Reduced binding of [3H]ketanserin to cortical 5-ht2 receptors in senile dementia of the Alzheimer type.

Authors:  G P Reynolds; L Arnold; M N Rossor; L L Iversen; C Q Mountjoy; M Roth
Journal:  Neurosci Lett       Date:  1984-01-27       Impact factor: 3.046

7.  Neurochemical characteristics of early and late onset types of Alzheimer's disease.

Authors:  M N Rossor; L L Iversen; G P Reynolds; C Q Mountjoy; M Roth
Journal:  Br Med J (Clin Res Ed)       Date:  1984-03-31

8.  Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease.

Authors:  C C Smith; D M Bowen; N R Sims; D Neary; A N Davison
Journal:  Brain Res       Date:  1983-03-28       Impact factor: 3.252

9.  The evoked release of endogenous amino acids from tissue prisms of human neocortex.

Authors:  C C Smith; D M Bowen; A N Davison
Journal:  Brain Res       Date:  1983-06-13       Impact factor: 3.252

10.  Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Authors:  D M Bowen; S J Allen; J S Benton; M J Goodhardt; E A Haan; A M Palmer; N R Sims; C C Smith; J A Spillane; M M Esiri; D Neary; J S Snowdon; G K Wilcock; A N Davison
Journal:  J Neurochem       Date:  1983-07       Impact factor: 5.372
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  10 in total

Review 1.  Is ammonia a pathogenetic factor in Alzheimer's disease?

Authors:  N Seiler
Journal:  Neurochem Res       Date:  1993-03       Impact factor: 3.996

Review 2.  Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer's Disease.

Authors:  Lan Guo; Jing Tian; Heng Du
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

3.  High performance liquid chromatography determination of L-glutamate, L-glutamine and glycine content in brain, cerebrospinal fluid and blood serum of patients affected by Alzheimer's disease.

Authors:  Tommaso Nuzzo; Andrea Mancini; Mattia Miroballo; Alessia Casamassa; Anna Di Maio; Giorgia Donati; Giulia Sansone; Lorenzo Gaetani; Federico Paolini Paoletti; Andrea Isidori; Paolo Calabresi; Francesco Errico; Lucilla Parnetti; Alessandro Usiello
Journal:  Amino Acids       Date:  2021-02-22       Impact factor: 3.520

Review 4.  Neuropathobiology of senile dementia and mechanism of action of nootropic drugs.

Authors:  O Benesová
Journal:  Drugs Aging       Date:  1994-04       Impact factor: 3.923

5.  Astrocytes and glutamate homoeostasis in Alzheimer's disease: a decrease in glutamine synthetase, but not in glutamate transporter-1, in the prefrontal cortex.

Authors:  Magdalena Kulijewicz-Nawrot; Eva Syková; Alexander Chvátal; Alexei Verkhratsky; José J Rodríguez
Journal:  ASN Neuro       Date:  2013-10-07       Impact factor: 4.146

6.  Stability and Solution Structure of Binary and Ternary Cu(II) Complexes with l-Glutamic Acid and Diamines as Well as Adducts in Metal-Free Systems in Aqueous Solution.

Authors:  Romualda Bregier-Jarzebowska
Journal:  J Solution Chem       Date:  2014-11-26       Impact factor: 1.677

7.  Abnormality in glutamine-glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study.

Authors:  K Hashimoto; D Bruno; J Nierenberg; C R Marmar; H Zetterberg; K Blennow; N Pomara
Journal:  Transl Psychiatry       Date:  2016-03-01       Impact factor: 6.222

8.  Serum Amino Acid Profiles in Normal Subjects and in Patients with or at Risk of Alzheimer Dementia.

Authors:  Gaetano Corso; Adriana Cristofano; Nadia Sapere; Giancarlo la Marca; Antonella Angiolillo; Michela Vitale; Roberto Fratangelo; Teresa Lombardi; Carola Porcile; Mariano Intrieri; Alfonso Di Costanzo
Journal:  Dement Geriatr Cogn Dis Extra       Date:  2017-05-04

Review 9.  Neuronal hyperexcitability in Alzheimer's disease: what are the drivers behind this aberrant phenotype?

Authors:  Helena Targa Dias Anastacio; Natalie Matosin; Lezanne Ooi
Journal:  Transl Psychiatry       Date:  2022-06-22       Impact factor: 7.989

10.  Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression.

Authors:  Caroline Madeira; Charles Vargas-Lopes; Carlos Otávio Brandão; Taylor Reis; Jerson Laks; Rogerio Panizzutti; Sergio T Ferreira
Journal:  Front Psychiatry       Date:  2018-11-06       Impact factor: 4.157
  10 in total

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