| Literature DB >> 28599188 |
Preetesh Jain1, Sa Wang2, Keyur P Patel2, Nawid Sarwari1, Jorge Cortes1, Hagop Kantarjian1, Srdan Verstovsek3.
Abstract
Mast cell leukemia (MCL) is a very rare subtype of systemic mastocytosis (SM). We have identified 13 such patients (5.9%) among 218 patients with SM seen at our institution between 1994 and 2016. Patients with MCL had poor survival (median 31.6 months); response to various therapies was rare and not durable. Clinical course may be affected by concurrent associated hematologic neoplasm and different genetic profiles. More research is required to decipher this rare and enigmatic SM subtype.Entities:
Keywords: Mast cell leukemia; Systemic mastocytosis
Mesh:
Year: 2017 PMID: 28599188 PMCID: PMC5573652 DOI: 10.1016/j.leukres.2017.05.018
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156