Ayse Sevgi Karadag1, Burak Bilgin2, Merih Banu Soylu3. 1. Department of Ophthalmology, School of Medicine, Adıyaman University, Adıyaman, Turkey. 2. Department of Ophthalmology, Medical Park Hospital, Gaziantep, Turkey. 3. Department of Ophthalmology, School of Medicine, Cukurova University, Adana, Turkey.
Abstract
PURPOSE: : We aimed to compare the retinal nerve fiber layer, ganglion cell layer, inner plexiform layer, and the choroid thickness between patients with Behcet disease and healthy subjects by using spectral domain optical coherence tomography (SD-OCT). METHODS: : Ninety eyes of 45 healthy subjects and 104 eyes of 52 patients with Behcet disease were included in this study. Rheumatoid factor and C-reactive protein levels were measured by blood testing in the patients. RESULTS: : The mean thickness of the retinal nerve fiber layer, ganglion cells layer, and inner plexiform layer were significantly lower in patients with Behcet's disease than in the healthy subjects. The mean choroidal thickness was significantly higher in the patients than in the healthy subjects. CONCLUSIONS: : SD-OCT was a useful and non-invasive tool for the detection of retinal nerve degeneration and choroidal changes in patients with Behcet disease even in the absence of ocular involvement.
PURPOSE: : We aimed to compare the retinal nerve fiber layer, ganglion cell layer, inner plexiform layer, and the choroid thickness between patients with Behcet disease and healthy subjects by using spectral domain optical coherence tomography (SD-OCT). METHODS: : Ninety eyes of 45 healthy subjects and 104 eyes of 52 patients with Behcet disease were included in this study. Rheumatoid factor and C-reactive protein levels were measured by blood testing in the patients. RESULTS: : The mean thickness of the retinal nerve fiber layer, ganglion cells layer, and inner plexiform layer were significantly lower in patients with Behcet's disease than in the healthy subjects. The mean choroidal thickness was significantly higher in the patients than in the healthy subjects. CONCLUSIONS: : SD-OCT was a useful and non-invasive tool for the detection of retinal nerve degeneration and choroidal changes in patients with Behcet disease even in the absence of ocular involvement.
Authors: Samantha Sze-Yee Lee; Gareth Lingham; David Alonso-Caneiro; Jason Charng; Fred Kuanfu Chen; Seyhan Yazar; David Anthony Mackey Journal: Transl Vis Sci Technol Date: 2021-03-01 Impact factor: 3.283