Literature DB >> 28589558

Potential applications and human biosafety of nanomaterials used in nanomedicine.

Hong Su1, Yafei Wang1, Yuanliang Gu1, Linda Bowman2, Jinshun Zhao1,2, Min Ding2.   

Abstract

With the rapid development of nanotechnology, potential applications of nanomaterials in medicine have been widely researched in recent years. Nanomaterials themselves can be used as image agents or therapeutic drugs, and for drug and gene delivery, biological devices, nanoelectronic biosensors or molecular nanotechnology. As the composition, morphology, chemical properties, implant sites as well as potential applications become more and more complex, human biosafety of nanomaterials for clinical use has become a major concern. If nanoparticles accumulate in the human body or interact with the body molecules or chemical components, health risks may also occur. Accordingly, the unique chemical and physical properties, potential applications in medical fields, as well as human biosafety in clinical trials are reviewed in this study. Finally, this article tries to give some suggestions for future work in nanomedicine research.
Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Entities:  

Keywords:  clinical trials; human biosafety; nanomaterials; nanomedicine products; nanoparticles (NPs); physical and chemical properties; potential applications

Mesh:

Year:  2017        PMID: 28589558      PMCID: PMC6506719          DOI: 10.1002/jat.3476

Source DB:  PubMed          Journal:  J Appl Toxicol        ISSN: 0260-437X            Impact factor:   3.446


  251 in total

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5.  The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin--the Aprepitant Protocol 052 Study Group.

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Review 7.  The dawning era of polymer therapeutics.

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8.  Nanoshell-enabled photonics-based imaging and therapy of cancer.

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9.  A phase II study of liposomal lurtotecan (OSI-211) in patients with topotecan resistant ovarian cancer.

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10.  Analysis of polyethylene-glycol-polylactide nano-dimension artificial red blood cells in maintaining systemic hemoglobin levels and prevention of methemoglobin formation.

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Journal:  Artif Cells Blood Substit Immobil Biotechnol       Date:  2003-08
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  15 in total

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2.  High-Throughput Screening Platform for Nanoparticle-Mediated Alterations of DNA Repair Capacity.

Authors:  Sneh M Toprani; Dimitrios Bitounis; Qiansheng Huang; Nathalia Oliveira; Kee Woei Ng; Chor Yong Tay; Zachary D Nagel; Philip Demokritou
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Review 4.  Evaluation of immunoresponses and cytotoxicity from skin exposure to metallic nanoparticles.

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Journal:  Int J Nanomedicine       Date:  2018-08-01

5.  Biosafety evaluation of Janus Fe3O4-TiO2 nanoparticles in Sprague Dawley rats after intravenous injection.

Authors:  Hong Su; Xin Song; Juan Li; Muhammad Zubair Iqbal; Samuel Selorm Fiati Kenston; Zhen Li; Aiguo Wu; Min Ding; Jinshun Zhao
Journal:  Int J Nanomedicine       Date:  2018-10-31

Review 6.  Advances in nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis.

Authors:  G Y Wang; S L Rayner; R Chung; B Y Shi; X J Liang
Journal:  Mater Today Bio       Date:  2020-05-04

Review 7.  External and Internal Stimuli-Responsive Metallic Nanotherapeutics for Enhanced Anticancer Therapy.

Authors:  Adityanarayan Mohapatra; Saji Uthaman; In-Kyu Park
Journal:  Front Mol Biosci       Date:  2021-01-11

Review 8.  The utility and risks of therapeutic nanotechnology in the retina.

Authors:  Melanie Scheive; Saeed Yazdani; Amir R Hajrasouliha
Journal:  Ther Adv Ophthalmol       Date:  2021-03-22

Review 9.  Recent Advances in Macrophage-Mediated Drug Delivery Systems.

Authors:  Tiantian Liang; Rongtao Zhang; Xianbin Liu; Qian Ding; Siqiong Wu; Chunhong Li; Yan Lin; Yun Ye; Zhirong Zhong; Meiling Zhou
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Review 10.  Drug Combinations in Breast Cancer Therapy.

Authors:  Funmilola A Fisusi; Emmanuel O Akala
Journal:  Pharm Nanotechnol       Date:  2019
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