| Literature DB >> 28589558 |
Hong Su1, Yafei Wang1, Yuanliang Gu1, Linda Bowman2, Jinshun Zhao1,2, Min Ding2.
Abstract
With the rapid development of nanotechnology, potential applications of nanomaterials in medicine have been widely researched in recent years. Nanomaterials themselves can be used as image agents or therapeutic drugs, and for drug and gene delivery, biological devices, nanoelectronic biosensors or molecular nanotechnology. As the composition, morphology, chemical properties, implant sites as well as potential applications become more and more complex, human biosafety of nanomaterials for clinical use has become a major concern. If nanoparticles accumulate in the human body or interact with the body molecules or chemical components, health risks may also occur. Accordingly, the unique chemical and physical properties, potential applications in medical fields, as well as human biosafety in clinical trials are reviewed in this study. Finally, this article tries to give some suggestions for future work in nanomedicine research.Entities:
Keywords: clinical trials; human biosafety; nanomaterials; nanomedicine products; nanoparticles (NPs); physical and chemical properties; potential applications
Mesh:
Year: 2017 PMID: 28589558 PMCID: PMC6506719 DOI: 10.1002/jat.3476
Source DB: PubMed Journal: J Appl Toxicol ISSN: 0260-437X Impact factor: 3.446