Literature DB >> 2858689

New orally active iron chelators.

G J Kontoghiorghes.   

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Year:  1985        PMID: 2858689     DOI: 10.1016/s0140-6736(85)91472-2

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


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  12 in total

1.  Comparative study of iron mobilization from haemosiderin, ferritin and iron(III) precipitates by chelators.

Authors:  G J Kontoghiorghes; S Chambers; A V Hoffbrand
Journal:  Biochem J       Date:  1987-01-01       Impact factor: 3.857

2.  Bifunctional 3-hydroxy-4-pyridinone derivatives as potential pharmaceuticals: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation with 67Ga.

Authors:  M Amélia Santos; Marco Gil; Lurdes Gano; Sílvia Chaves
Journal:  J Biol Inorg Chem       Date:  2005-09-23       Impact factor: 3.358

Review 3.  Deferiprone: A Forty-Year-Old Multi-Targeting Drug with Possible Activity against COVID-19 and Diseases of Similar Symptomatology.

Authors:  George J Kontoghiorghes
Journal:  Int J Mol Sci       Date:  2022-06-16       Impact factor: 6.208

4.  The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.

Authors:  J Y Jeremy; G J Kontoghiorghes; A V Hoffbrand; P Dandona
Journal:  Biochem J       Date:  1988-08-15       Impact factor: 3.857

Review 5.  Oral iron chelation: a review with special emphasis on Indian work on deferiprone (L1).

Authors:  M B Agarwal
Journal:  Indian J Pediatr       Date:  1993 Jul-Aug       Impact factor: 1.967

Review 6.  Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine.

Authors:  George J Kontoghiorghes; Katia Neocleous; Annita Kolnagou
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

7.  Iron mobilization from ferritin using alpha-oxohydroxy heteroaromatic chelators.

Authors:  G J Kontoghiorghes
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

8.  Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.

Authors:  G J Kontoghiorghes; M A Aldouri; A V Hoffbrand; J Barr; B Wonke; T Kourouclaris; L Sheppard
Journal:  Br Med J (Clin Res Ed)       Date:  1987-12-12

9.  Yersiniabactin reduces the respiratory oxidative stress response of innate immune cells.

Authors:  Armand Paauw; Maurine A Leverstein-van Hall; Kok P M van Kessel; Jan Verhoef; Ad C Fluit
Journal:  PLoS One       Date:  2009-12-29       Impact factor: 3.240

10.  Deferiprone in the treatment of transfusion-dependent thalassemia: a review and perspective.

Authors:  Renzo Galanello
Journal:  Ther Clin Risk Manag       Date:  2007-10       Impact factor: 2.423

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