Literature DB >> 28585108

Contribution of Malabsorption to Weight Loss After Roux-en-Y Gastric Bypass: a Systematic Review.

Kamal K Mahawar1, Alistair J Sharples2.   

Abstract

Roux-en-Y gastric bypass (RYGB) is traditionally classified as a combined restrictive and malabsorptive operation. This notion of the operation influences its technical variations and revisions for patients who do not achieve significant weight loss after this surgery. There is an increasing body of literature suggesting a role for appetite suppression mediated by neuro-hormonal signals after RYGB. The purpose of this paper was to systematically review published English language scientific literature to determine the role of malabsorption towards weight loss achieved with RYGB. This review finds that there is little or no malabsorption of carbohydrates or protein after RYGB but there is some fat malabsorption. Overall, malabsorption makes a little (approximately 11.0% in the early period) overall contribution to weight loss after RYGB.

Entities:  

Keywords:  Absorption; Carbohydrate; Fat; Gastric bypass; Malabsorption; Malabsorptive; Protein; Roux-en-Y-gastric bypass

Mesh:

Year:  2017        PMID: 28585108     DOI: 10.1007/s11695-017-2762-y

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  35 in total

1.  Changes in intestinal permeability after Roux-en-Y gastric bypass.

Authors:  Alexandre Lages Savassi-Rocha; Marco Túlio Costa Diniz; Eduardo Garcia Vilela; Maria de Fátima Haueisen Sander Diniz; Soraya Rodrigues de Almeida Sanches; Aloísio Sales da Cunha; Maria de Lourdes de Abreu Ferrari; Henrique Oswaldo da Gama Torres; Bruno Antonio Maciente; Gabriela Santana Ataliba; Paloma Maciel Araújo; Taciana Bretas Guerra; Inara Kellen Fonseca Balbino
Journal:  Obes Surg       Date:  2014-02       Impact factor: 4.129

2.  Enhanced thermic effect of food after Roux-en-Y gastric bypass surgery.

Authors:  Britta Wilms; Barbara Ernst; Sebastian M Schmid; Martin Thurnheer; Bernd Schultes
Journal:  J Clin Endocrinol Metab       Date:  2013-07-03       Impact factor: 5.958

3.  Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss.

Authors:  Blandine Laferrère; David Reilly; Sara Arias; Nicholas Swerdlow; Prakash Gorroochurn; Baani Bawa; Mousumi Bose; Julio Teixeira; Robert D Stevens; Brett R Wenner; James R Bain; Michael J Muehlbauer; Andrea Haqq; Lillian Lien; Svati H Shah; Laura P Svetkey; Christopher B Newgard
Journal:  Sci Transl Med       Date:  2011-04-27       Impact factor: 17.956

4.  Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding.

Authors:  Jussi Pihlajamäki; Sari Grönlund; Marko Simonen; Pirjo Käkelä; Leena Moilanen; Matti Pääkkönen; Elina Pirinen; Marjukka Kolehmainen; Vesa Kärjä; Sakari Kainulainen; Matti Uusitupa; Esko Alhava; Tatu A Miettinen; Helena Gylling
Journal:  Metabolism       Date:  2009-12-16       Impact factor: 8.694

5.  Upregulation of intestinal glucose transporters after Roux-en-Y gastric bypass to prevent carbohydrate malabsorption.

Authors:  Nam Q Nguyen; Tamara L Debreceni; Jenna E Bambrick; Bridgette Chia; Adam M Deane; Gary Wittert; Chris K Rayner; Michael Horowitz; Richard L Young
Journal:  Obesity (Silver Spring)       Date:  2014-07-02       Impact factor: 5.002

6.  Essential Fatty Acid Plasma Profiles Following Gastric Bypass and Adjusted Gastric Banding Bariatric Surgeries.

Authors:  Rebekah Forbes; Danijela Gasevic; Emily M Watson; Thomas R Ziegler; Edward Lin; John R Burgess; Nana Gletsu-Miller
Journal:  Obes Surg       Date:  2016-06       Impact factor: 4.129

Review 7.  Small Bowel Limb Lengths and Roux-en-Y Gastric Bypass: a Systematic Review.

Authors:  Kamal K Mahawar; Parveen Kumar; Chetan Parmar; Yitka Graham; William R J Carr; Neil Jennings; Norbert Schroeder; Shlok Balupuri; Peter K Small
Journal:  Obes Surg       Date:  2016-03       Impact factor: 4.129

8.  Effects of gastric bypass and gastric banding on glucose kinetics and gut hormone release.

Authors:  Frédérique Rodieux; Vittorio Giusti; David A D'Alessio; Michel Suter; Luc Tappy
Journal:  Obesity (Silver Spring)       Date:  2008-02       Impact factor: 5.002

9.  Early improvement of postprandial lipemia after bariatric surgery in obese type 2 diabetic patients.

Authors:  E Griffo; G Nosso; R Lupoli; M Cotugno; G Saldalamacchia; G Vitolo; L Angrisani; P P Cutolo; A A Rivellese; B Capaldo
Journal:  Obes Surg       Date:  2014-05       Impact factor: 4.129

10.  Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety.

Authors:  C M Borg; C W le Roux; M A Ghatei; S R Bloom; A G Patel; S J B Aylwin
Journal:  Br J Surg       Date:  2006-02       Impact factor: 6.939

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  19 in total

1.  One Anastomosis Gastric Bypass Performed with a 150-cm Biliopancreatic Limb Delivers Weight Loss Outcomes Similar to Those with a 200-cm Biliopancreatic Limb at 18 -24 Months.

Authors:  Maureen Boyle; Kamal Mahawar
Journal:  Obes Surg       Date:  2020-04       Impact factor: 4.129

2.  A systematic review of the effect of gastric pouch and/or gastrojejunostomy (stoma) size on weight loss outcomes with Roux-en-Y gastric bypass.

Authors:  Kamal Mahawar; Alistair J Sharples; Yitka Graham
Journal:  Surg Endosc       Date:  2019-11-19       Impact factor: 4.584

Review 3.  Changes in Bile Acid Metabolism, Transport, and Signaling as Central Drivers for Metabolic Improvements After Bariatric Surgery.

Authors:  Matthew G Browning; Bernardo M Pessoa; Jad Khoraki; Guilherme M Campos
Journal:  Curr Obes Rep       Date:  2019-06

4.  Roux-en-Y Gastric Bypass Improves Metabolic Conditions in Association with Increased Serum Bile Acids Level and Hepatic Farnesoid X Receptor Expression in a T2DM Rat Model.

Authors:  Yong Yan; Yanhua Sha; Xianzhang Huang; Wei Yuan; Fan Wu; Jinsong Hong; Shaomei Fang; Bo Huang; Cheng Hu; Bailin Wang; Xueli Zhang
Journal:  Obes Surg       Date:  2019-09       Impact factor: 4.129

Review 5.  Proceedings of the 2017 ASPEN Research Workshop-Gastric Bypass: Role of the Gut.

Authors:  Ajay Kumar Jain; Carel W le Roux; Puneet Puri; Ali Tavakkoli; Nana Gletsu-Miller; Blandine Laferrère; Richard Kellermayer; John K DiBaise; Robert G Martindale; Bruce M Wolfe
Journal:  JPEN J Parenter Enteral Nutr       Date:  2018-02       Impact factor: 4.016

6.  Consistent gut bacterial and short-chain fatty acid signatures in hypoabsorptive bariatric surgeries correlate with metabolic benefits in rats.

Authors:  Paulette Mukorako; Natacha Lemoine; Laurent Biertho; Stéfane Lebel; Marie-Claude Roy; Julie Plamondon; André Tchernof; Thibault V Varin; Fernando F Anhê; David H St-Pierre; André Marette; Denis Richard
Journal:  Int J Obes (Lond)       Date:  2021-10-22       Impact factor: 5.095

7.  Proximal Roux-en-Y gastric bypass: Addressing the myth of limb length.

Authors:  Bestoun Ahmed; Wendy C King; William Gourash; Amanda Hinerman; Steven H Belle; Alfons Pomp; Walter J Pories; Anita P Courcoulas
Journal:  Surgery       Date:  2019-08-01       Impact factor: 3.982

8.  The First Consensus Statement on One Anastomosis/Mini Gastric Bypass (OAGB/MGB) Using a Modified Delphi Approach.

Authors:  Kamal K Mahawar; Jacques Himpens; Scott A Shikora; Jean-Marc Chevallier; Mufazzal Lakdawala; Maurizio De Luca; Rudolf Weiner; Ali Khammas; Kuldeepak Singh Kular; Mario Musella; Gerhard Prager; Mohammad Khalid Mirza; Miguel Carbajo; Lilian Kow; Wei-Jei Lee; Peter K Small
Journal:  Obes Surg       Date:  2018-02       Impact factor: 4.129

9.  Changes in Bone Mineral Density Following Weight Loss Induced by One-Anastomosis Gastric Bypass in Patients with Vitamin D Supplementation.

Authors:  Maria Luger; Renate Kruschitz; Eva Winzer; Karin Schindler; Igor Grabovac; Franz Kainberger; Michael Krebs; Friedrich Hoppichler; Felix Langer; Gerhard Prager; Rodrig Marculescu; Bernhard Ludvik
Journal:  Obes Surg       Date:  2018-11       Impact factor: 4.129

Review 10.  The Importance of Intestinal Length in Triglyceride Metabolism and in Predicting the Outcomes of Comorbidities in Laparoscopic Roux-en-Y Gastric Bypass-a Narrative Review.

Authors:  Pirjo Käkelä; Tuomo Rantanen; Kirsi A Virtanen
Journal:  Obes Surg       Date:  2021-04-29       Impact factor: 4.129

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