Literature DB >> 28573441

Sociodemographic and Clinical Determinants of Quality of Life of Patients with Non-small Cell Lung Cancer.

Mariusz Chabowski1, Jacek Polański2, Grzegorz Mazur3, Dariusz Janczak4, Joanna Rosińczuk5.   

Abstract

Non-small cell lung cancer (NSCLC) is a serious health problem. Identifying factors affecting quality of life (QoL) may help modify risk factors and improve survival. The study included 180 patients treated for NSCLC in the Lower Silesian Center of Lung Diseases between January and December 2015. QoL was assessed with QLQ-C30 and QLQ-LC13 scales. General physical functioning was measured with the ECOG Performance Status scale. The clinical and sociodemographic data were retrieved from medical records. The influence of clinical and sociodemographic factors on QoL was examined. NSCLC reduced the global QoL (47.1 ± 23.4) and emotional functioning (57.8 ± 28.8); cognitive functioning was affected in least (76.0 ± 21.0). The patients reported fatigue (42.2 ± 26.2), sleep problems (42.0 ± 30.8), cough (49.8 ± 24.0), and taking analgesics (50.3 ± 37.1) as the most limiting factors. The worsening of a health condition expressed by the length of malignant disease; the presence of comorbidities, metastases, the cluster of symptoms, worse spirometric indices, and living alone had a negative influence on QoL. In conclusion, patients with NSCLC experience reduced QoL and emotional functioning. Proper treatment of comorbidities and symptom management may improve QoL in these patients.

Entities:  

Keywords:  Cognitive functioning; NSCLC; Performance status; Physical functioning; Quality of life; Socioeconomic factors

Mesh:

Year:  2017        PMID: 28573441     DOI: 10.1007/5584_2017_36

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  5 in total

1.  Comorbidities, treatment-related consequences, and health-related quality of life among rural cancer survivors.

Authors:  Shaila M Strayhorn; Leslie R Carnahan; Kristine Zimmermann; Theresa A Hastert; Karriem S Watson; Carol Estwing Ferrans; Yamilé Molina
Journal:  Support Care Cancer       Date:  2019-07-24       Impact factor: 3.603

2.  Dynamic changes in quality of life after three first-line therapies for EGFR mutation-positive advanced non-small-cell lung cancer.

Authors:  Szu-Chun Yang; Chien-Chung Lin; Wu-Wei Lai; Sheng-Mao Chang; Jing-Shiang Hwang; Wu-Chou Su; Jung-Der Wang
Journal:  Ther Adv Med Oncol       Date:  2018-02-05       Impact factor: 8.168

3.  Satisfactory results of a psychometric analysis and calculation of minimal clinically important differences of the World Health Organization quality of life-BREF questionnaire in an observational cohort study with lung cancer and mesothelioma patients.

Authors:  Mark de Mol; Sabine Visser; Joachim G J V Aerts; Paul Lodder; Jolanda de Vries; Brenda L den Oudsten
Journal:  BMC Cancer       Date:  2018-11-26       Impact factor: 4.430

4.  The effect of coping strategy on quality of life in patients with NSCLC.

Authors:  Mariusz Chabowski; Beata Jankowska-Polańska; Katarzyna Lomper; Dariusz Janczak
Journal:  Cancer Manag Res       Date:  2018-10-01       Impact factor: 3.989

5.  Health-related quality of life in Chinese inpatients with lung cancer treatedin large general hospitals: across-sectional study.

Authors:  Wen Gu; Yan-Min Xu; Bao-Liang Zhong
Journal:  BMJ Open       Date:  2018-04-24       Impact factor: 2.692

  5 in total

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