Literature DB >> 2856253

Co-amplification of integrated hepatitis B virus DNA and transforming gene hst-1 in a hepatocellular carcinoma.

I Hatada1, T Tokino, T Ochiya, K Matsubara.   

Abstract

Transforming activity was detected in a hepatocellular carcinoma (HCC) carrying four integrated hepatitis B virus (HBV) DNA. This transforming gene was identified as hst-1, that lies in chromosome 11, band q13.3. One of the integrated HBV DNAs was found to lie close to the hst-1, and the hst-1 and the integrated HBV DNA were found to be co-amplified. The region of the amplification was limited. A model has been proposed that correlates the viral integration, amplification and activation of an oncogene.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2856253

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  16 in total

1.  Mapping of 262 DNA markers into 24 intervals on human chromosome 11.

Authors:  A Tanigami; T Tokino; S Takiguchi; M Mori; T Glaser; J W Park; C Jones; Y Nakamura
Journal:  Am J Hum Genet       Date:  1992-01       Impact factor: 11.025

2.  Chromosomal sites for hepatitis B virus integration in human hepatocellular carcinoma.

Authors:  T Tokino; K Matsubara
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103

Review 3.  Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma.

Authors:  M A Feitelson; L X Duan
Journal:  Am J Pathol       Date:  1997-04       Impact factor: 4.307

Review 4.  Cyclin D1 and human neoplasia.

Authors:  R Donnellan; R Chetty
Journal:  Mol Pathol       Date:  1998-02

5.  Double-stranded linear duck hepatitis B virus (DHBV) stably integrates at a higher frequency than wild-type DHBV in LMH chicken hepatoma cells.

Authors:  S S Gong; A D Jensen; C J Chang; C E Rogler
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

Review 6.  The detection of hepatitis B virus (HBV) in HBsAG negative individuals with primary liver cancer.

Authors:  P Paterlini; C Bréchot
Journal:  Dig Dis Sci       Date:  1991-08       Impact factor: 3.199

7.  Loss and acquisition of duck hepatitis B virus integrations in lineages of LMH-D2 chicken hepatoma cells.

Authors:  S S Gong; A D Jensen; C E Rogler
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

8.  Amplification and overexpression of the EMS 1 oncogene, a possible prognostic marker, in human hepatocellular carcinoma.

Authors:  Bao-Zhu Yuan; Xiaoling Zhou; Drazen B Zimonjic; Marian E Durkin; Nicholas C Popescu
Journal:  J Mol Diagn       Date:  2003-02       Impact factor: 5.568

Review 9.  Hepatitis B virus infection and primary hepatocellular carcinoma.

Authors:  M Feitelson
Journal:  Clin Microbiol Rev       Date:  1992-07       Impact factor: 26.132

10.  The mouse homologue of hst/k-FGF: sequence, genome organization and location relative to int-2.

Authors:  S Brookes; R Smith; J Thurlow; C Dickson; G Peters
Journal:  Nucleic Acids Res       Date:  1989-06-12       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.