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Literature DB >> 1346079

Mapping of 262 DNA markers into 24 intervals on human chromosome 11.

A Tanigami¹, T Tokino, S Takiguchi, M Mori, T Glaser, J W Park, C Jones, Y Nakamura.

Abstract

We have extended our mapping effort on human chromosome 11 to encompass a total of 262 DNA markers, which have been mapped into 24 intervals on chromosome 11; 123 of the markers reveal RFLPs. These clones are scattered throughout the chromosome, although some clustering occurs in R-positive bands (p15.1, p11.2, q13, and q23.3). Fifty-two of the markers were found to contain DNA sequences conserved in Chinese hamster, and some of these 52 also cross-hybridized with DNA from other mammals and/or chicken. As the length of chromosome 11 is estimated at nearly 130 cM, the average distance between RFLP markers is roughly 1 cM. The large panel of DNA markers on our map should contribute to investigations of hereditary diseases on this chromosome, and it will also provide reagents for constructing either fine-scale linkage and physical maps or contig maps of cosmids or yeast artificial chromosomes.

Entities: Disease Gene Species

Mesh：

Substances：
Genetic Markers
DNA

Year: 1992 PMID： 1346079 PMCID： PMC1682531

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

30 in total

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Journal: Genomics Date: 1991-03 Impact factor: 5.736

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Journal: Nature Date: 1987 Oct 15-21 Impact factor: 49.962

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Journal: Am J Hum Genet Date: 1989-05 Impact factor: 11.025

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Journal: Proc Natl Acad Sci U S A Date: 1986-08 Impact factor: 11.205

5. Numerical chromosome 1, 7, 9, and 11 aberrations in bladder cancer detected by in situ hybridization.

Authors: A H Hopman; O Moesker; A W Smeets; R P Pauwels; G P Vooijs; F C Ramaekers
Journal: Cancer Res Date: 1991-01-15 Impact factor: 12.701

6. Co-amplification of integrated hepatitis B virus DNA and transforming gene hst-1 in a hepatocellular carcinoma.

Authors: I Hatada; T Tokino; T Ochiya; K Matsubara
Journal: Oncogene Date: 1988-11 Impact factor: 9.867

7. Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23.

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Journal: Genomics Date: 1990-01 Impact factor: 5.736

8. Amplification of human int-2 in breast cancers and squamous carcinomas.

Authors: D J Zhou; G Casey; M J Cline
Journal: Oncogene Date: 1988-03 Impact factor: 9.867

9. Loss of genes on the short arm of chromosome 11 in bladder cancer.

Authors: E R Fearon; A P Feinberg; S H Hamilton; B Vogelstein
Journal: Nature Date: 1985 Nov 28-Dec 4 Impact factor: 49.962

10. Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.

Authors: R A Gatti; I Berkel; E Boder; G Braedt; P Charmley; P Concannon; F Ersoy; T Foroud; N G Jaspers; K Lange
Journal: Nature Date: 1988-12-08 Impact factor: 49.962

9 in total

1. Characterization of a cosmid library from flow-sorted chromosomes 11.

Authors: B H Weber; H Stöhr; I Siedlaczck; J L Longmire; L L Deaven; A M Duncan; O Riess
Journal: Chromosome Res Date: 1994-05 Impact factor: 5.239

2. High-resolution meiotic and physical mapping of the best vitelliform macular dystrophy (VMD2) locus to pericentromeric chromosome 11.

Authors: B H Weber; G Vogt; H Stöhr; S Sander; D Walker; C Jones
Journal: Am J Hum Genet Date: 1994-12 Impact factor: 11.025

3. Genetic screening to identify the gene carrier in Italian and German kindreds affected by multiple endocrine neoplasia type 1 (MEN 1) syndrome.

Authors: A Morelli; A Falchetti; R Castello; L Furlani; P Tomassetti; F Tonelli; A Frilling; M Serio; M L Brandi
Journal: J Endocrinol Invest Date: 1995-05 Impact factor: 4.256

4. Subregional physical mapping of an alpha B-crystallin sequence and of a new expressed sequence D11S877E to human 11q.

Authors: C Jeanpierre; E Austruy; O Delattre; C Jones; C Junien
Journal: Mamm Genome Date: 1993 Impact factor: 2.957

5. A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci.

Authors: C W Richard; M Boehnke; D J Berg; J H Lichy; T C Meeker; E Hauser; R M Myers; D R Cox
Journal: Am J Hum Genet Date: 1993-05 Impact factor: 11.025

6. Schizophrenia-associated chromosome 11q21 translocation: identification of flanking markers and development of chromosome 11q fragment hybrids as cloning and mapping resources.

Authors: J M Fletcher; K Evans; D Baillie; P Byrd; D Hanratty; S Leach; C Julier; J R Gosden; W Muir; D J Porteous
Journal: Am J Hum Genet Date: 1993-03 Impact factor: 11.025