Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Unexpected mutations after CRISPR-Cas9 editing in vivo.

Literature DB >> 28557981

Unexpected mutations after CRISPR-Cas9 editing in vivo.

Kellie A Schaefer^1,2, Wen-Hsuan Wu^3,4, Diana F Colgan¹, Stephen H Tsang^3,4, Alexander G Bassuk^5,6, Vinit B Mahajan^1,7.

Abstract

Entities: Disease Gene Species

Year: 2017 PMID： 28557981 PMCID： PMC5796662 DOI： 10.1038/nmeth.4293

Source DB: PubMed Journal: Nat Methods ISSN： 1548-7091 Impact factor: 28.547

× No keyword cloud information.

6 in total

1. Estimate of the mutation rate per nucleotide in humans.

Authors: M W Nachman; S L Crowell
Journal: Genetics Date: 2000-09 Impact factor: 4.562

Review 2. Non-coding RNA.

Authors: John S Mattick; Igor V Makunin
Journal: Hum Mol Genet Date: 2006-04-15 Impact factor: 6.150

3. Analysis of genetic inheritance in a family quartet by whole-genome sequencing.

Authors: Jared C Roach; Gustavo Glusman; Arian F A Smit; Chad D Huff; Robert Hubley; Paul T Shannon; Lee Rowen; Krishna P Pant; Nathan Goodman; Michael Bamshad; Jay Shendure; Radoje Drmanac; Lynn B Jorde; Leroy Hood; David J Galas
Journal: Science Date: 2010-03-10 Impact factor: 47.728

4. CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa.

Authors: Wen-Hsuan Wu; Yi-Ting Tsai; Sally Justus; Ting-Ting Lee; Lijuan Zhang; Chyuan-Sheng Lin; Alexander G Bassuk; Vinit B Mahajan; Stephen H Tsang
Journal: Mol Ther Date: 2016-05-20 Impact factor: 11.454

5. Off-target mutations are rare in Cas9-modified mice.

Authors: Vivek Iyer; Bin Shen; Wensheng Zhang; Alex Hodgkins; Thomas Keane; Xingxu Huang; William C Skarnes
Journal: Nat Methods Date: 2015-06 Impact factor: 28.547

Review 6. Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9.

Authors: Taeyoung Koo; Jungjoon Lee; Jin-Soo Kim
Journal: Mol Cells Date: 2015-05-19 Impact factor: 5.034

6 in total

106 in total

Review 1. Transposase-mediated gene modulation in the placenta.

Authors: Marlee Elston; Johann Urschitz
Journal: Placenta Date: 2017-07-29 Impact factor: 3.481

Review 2. Gene-edited CRISPy Critters for alcohol research.

Authors: Gregg E Homanics
Journal: Alcohol Date: 2018-03-07 Impact factor: 2.405

3. Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology.

Authors: Silvia Pittolo; Hyojung Lee; Anna Lladó; Sébastien Tosi; Miquel Bosch; Lídia Bardia; Xavier Gómez-Santacana; Amadeu Llebaria; Eduardo Soriano; Julien Colombelli; Kira E Poskanzer; Gertrudis Perea; Pau Gorostiza
Journal: Proc Natl Acad Sci U S A Date: 2019-06-13 Impact factor: 11.205

4. Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9.

Authors: Ranjan Batra; David A Nelles; Elaine Pirie; Steven M Blue; Ryan J Marina; Harrison Wang; Isaac A Chaim; James D Thomas; Nigel Zhang; Vu Nguyen; Stefan Aigner; Sebastian Markmiller; Guangbin Xia; Kevin D Corbett; Maurice S Swanson; Gene W Yeo
Journal: Cell Date: 2017-08-10 Impact factor: 41.582

5. Inconclusive studies on possible CRISPR-Cas off-targets should moderate expectations about enzymes that have evolved to be non-specific.

Authors: Sandeep Chakraborty
Journal: J Biosci Date: 2018-06 Impact factor: 1.826