Literature DB >> 28556608

Impact of a National Controlled Donation After Circulatory Death (DCD) Program on Organ Donation in the United Kingdom: A 10-Year Study.

R Hodgson1,2, A L Young2, M A Attia2, J P A Lodge2.   

Abstract

Organ transplantation is the most successful treatment for some forms of organ failure, yet a lack of organs means many die on the waiting list. In the United Kingdom, the Organ Donation Taskforce was set up to identify barriers to organ donation and in 2008 released its first report (Organ Donation Taskforce Report; ODTR). This study assesses the success since the ODTR and examines the impact of the United Kingdom's controlled donation after circulatory death (DCD) program and the controversies surrounding it. There were 12 864 intended donation after brain death (DBD) or DCD donors from April 2004 to March 2014. When the 5 years preceding the ODTR was compared to the 5 years following, intended DCD donors increased 292% (1187 to 4652), and intended DBD donors increased 11% (3327 to 3698). Organs retrieved per intended DBD donor remained static (3.30 to 3.26), whereas there was a decrease in DCD (1.54 to 0.99) due to a large rise in donors who did not proceed to donation (325 to 2464). The majority of DCD donors who proceeded did so within 30 min from time of withdrawal. Our study suggests further work on converting eligible referrals to organ donation and exploring methods of converting DCD to DBD donors.
© 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research/practice; donors and donation; donors and donation: deceased; donors and donation: donation after brain death (DBD); donors and donation: donation after circulatory death (DCD); health services and outcomes research; organ procurement and allocation; organ transplantation in general

Mesh:

Year:  2017        PMID: 28556608     DOI: 10.1111/ajt.14374

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  5 in total

1.  Wide variation in the percentage of donation after circulatory death donors across donor service areas - a potential target for improvement.

Authors:  Elizabeth M Sonnenberg; Jesse Y Hsu; Peter P Reese; David Goldberg; Peter L Abt
Journal:  Transplantation       Date:  2019-10-21       Impact factor: 4.939

2.  Human liver stem cell-derived extracellular vesicles reduce injury in a model of normothermic machine perfusion of rat livers previously exposed to a prolonged warm ischemia.

Authors:  Nicola De Stefano; Victor Navarro-Tableros; Dorotea Roggio; Alberto Calleri; Federica Rigo; Ezio David; Alessandro Gambella; Daniela Bassino; Antonio Amoroso; Damiano Patrono; Giovanni Camussi; Renato Romagnoli
Journal:  Transpl Int       Date:  2021-09       Impact factor: 3.842

Review 3.  Donation after circulatory death and lung transplantation.

Authors:  Pedro Augusto Reck Dos Santos; Paulo José Zimermann Teixeira; Daniel Messias de Moraes Neto; Marcelo Cypel
Journal:  J Bras Pneumol       Date:  2022-04-20       Impact factor: 2.800

4.  Wide Variation in the Percentage of Donation After Circulatory Death Donors Across Donor Service Areas: A Potential Target for Improvement.

Authors:  Elizabeth M Sonnenberg; Jesse Y Hsu; Peter P Reese; David S Goldberg; Peter L Abt
Journal:  Transplantation       Date:  2020-08       Impact factor: 5.385

5.  First Scandinavian Protocol for Controlled Donation After Circulatory Death Using Normothermic Regional Perfusion.

Authors:  Stein Foss; Espen Nordheim; Dag W Sørensen; Torgunn B Syversen; Karsten Midtvedt; Anders Åsberg; Thorleif Dahl; Per A Bakkan; Aksel E Foss; Odd R Geiran; Arnt E Fiane; Pål-Dag Line
Journal:  Transplant Direct       Date:  2018-06-13
  5 in total

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