Samira Helena João-Souza1, Sávio José C Bezerra2, Patrícia Moreira de Freitas3, Nelson B de Lima4, Ana Cecília Corrêa Aranha5, Anderson T Hara6, Taís Scaramucci7. 1. Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, Cidade Universitária, Zip code: 05508-000, São Paulo, SP, Brazil. Electronic address: samyhelen@hotmail.com. 2. Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, Cidade Universitária, Zip code: 05508-000, São Paulo, SP, Brazil. Electronic address: saviocbezerra@hotmail.com. 3. Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, Cidade Universitária, Zip code: 05508-000, São Paulo, SP, Brazil. Electronic address: pfreitas@usp.br. 4. Centro de Ciência e Tecnologia dos Materiais, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Butantã, P.O. Box 11049, São Paulo, SP 05422-970, Brazil. Electronic address: nblima@ipen.br. 5. Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, Cidade Universitária, Zip code: 05508-000, São Paulo, SP, Brazil. Electronic address: acca@usp.br. 6. Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University, School of Dentistry, 415 Lansing street, 46202-2855, Indianapolis, IN, USA. Electronic address: ahara@iu.edu. 7. Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, Cidade Universitária, Zip code: 05508-000, São Paulo, SP, Brazil. Electronic address: tais.sca@usp.br.
Abstract
OBJECTIVE: To evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225ppm of fluoride), sodium fluoride+stannous chloride (F+Sn: 225ppm of fluoride+800ppm of stannous), sodium fluoride+stannous chloride+sodium linear polyphosphate (F+Sn+LPP: 225ppm of fluoride+800ppm of stannous+2% of sodium linear polyphosphate), and deionized water (C: control), using a four-phase, single-blind, crossover in situ clinical trial. METHODS: In each phase, 12 volunteers wore appliances containing 4 enamel specimens, which were submitted to a 5-day erosion-remineralization phase that consisted of 2h of salivary pellicle formation with the appliance in situ, followed by 2min extra-oral immersion in 1% citric acid (pH 2.4), 6x/day, with 90min of exposure to saliva in situ between the challenges. Treatment with the test solutions was performed extra-orally for 2 min, 2x/day. At the end of the experiment, surface loss (SL, in μm) was evaluated by optical profilometry. Data were analyzed using ANOVA and Tukey tests (α=0.05). The surface of additional specimens was evaluated by x-ray diffraction after treatments (n=3). RESULTS: C (mean SL±standard-deviation: 5.97±1.70) and F (5.36±1.59) showed the highest SL, with no significant difference between them (p>0.05). F+Sn (2.68±1.62) and F+Sn+LPP (2.10±0.95) did not differ from each other (p>0.05), but presented lower SL than the other groups (P<0.05). Apatite and stannous deposits on specimen surfaces were identified in the x-ray analysis for F+Sn and F+Sn+LPP. CONCLUSIONS: Sodium fluoride solution exhibited no significant anti-erosive effect. The combination between sodium fluoride and stannous chloride reduced enamel erosion, irrespective of the presence of linear sodium polyphosphate. CLINICAL SIGNIFICANCE: Under highly erosive conditions, sodium fluoride rinse may not be a suitable alternative to prevent enamel erosion. A rinse containing sodium fluoride and stannous chloride was shown to be a better treatment option, which was not further improved by addition of the sodium linear polyphosphate.
OBJECTIVE: To evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225ppm of fluoride), sodium fluoride+stannous chloride (F+Sn: 225ppm of fluoride+800ppm of stannous), sodium fluoride+stannous chloride+sodium linear polyphosphate (F+Sn+LPP: 225ppm of fluoride+800ppm of stannous+2% of sodium linear polyphosphate), and deionized water (C: control), using a four-phase, single-blind, crossover in situ clinical trial. METHODS: In each phase, 12 volunteers wore appliances containing 4 enamel specimens, which were submitted to a 5-day erosion-remineralization phase that consisted of 2h of salivary pellicle formation with the appliance in situ, followed by 2min extra-oral immersion in 1% citric acid (pH 2.4), 6x/day, with 90min of exposure to saliva in situ between the challenges. Treatment with the test solutions was performed extra-orally for 2 min, 2x/day. At the end of the experiment, surface loss (SL, in μm) was evaluated by optical profilometry. Data were analyzed using ANOVA and Tukey tests (α=0.05). The surface of additional specimens was evaluated by x-ray diffraction after treatments (n=3). RESULTS: C (mean SL±standard-deviation: 5.97±1.70) and F (5.36±1.59) showed the highest SL, with no significant difference between them (p>0.05). F+Sn (2.68±1.62) and F+Sn+LPP (2.10±0.95) did not differ from each other (p>0.05), but presented lower SL than the other groups (P<0.05). Apatite and stannous deposits on specimen surfaces were identified in the x-ray analysis for F+Sn and F+Sn+LPP. CONCLUSIONS:Sodium fluoride solution exhibited no significant anti-erosive effect. The combination between sodium fluoride and stannous chloride reduced enamel erosion, irrespective of the presence of linear sodium polyphosphate. CLINICAL SIGNIFICANCE: Under highly erosive conditions, sodium fluoride rinse may not be a suitable alternative to prevent enamel erosion. A rinse containing sodium fluoride and stannous chloride was shown to be a better treatment option, which was not further improved by addition of the sodium linear polyphosphate.
Authors: Raquel Marianna Lopes; T Scaramucci; Clandler L Walker; S A Feitosa; Ana Cecilia Correa Aranha Journal: Clin Oral Investig Date: 2021-05-11 Impact factor: 3.573
Authors: Sávio José Cardoso Bezerra; Ítallo Emídio Lira Viana; Idalina Vieira Aoki; Maria Angela Pita Sobral; Alessandra Buhler Borges; Anderson T Hara; Taís Scaramucci Journal: J Mater Sci Mater Med Date: 2021-07-01 Impact factor: 3.896