Literature DB >> 28551734

Alopecia Areata: An Update on Treatment Options for Children.

Lauren Peloquin1, Leslie Castelo-Soccio2.   

Abstract

Pediatric alopecia areata is a spectrum of autoimmune non-scarring alopecia in which some patients lose small patches of hair from their scalp but others lose more or all of the hair from the scalp and body, including eyebrows and eyelashes. Few studies have looked at therapies for this disorder in children, so much of the data are derived from adult literature and describe off-label use of medication. Generally, topical therapies consisting of topical steroids and topical irritating compounds/contact sensitizers are used. Systemic therapies that block the immune system, including Janus kinase (JAK) inhibitors, have also been used in this disease. This paper reviews the data on therapy for alopecia areata in pediatric patients.

Entities:  

Mesh:

Substances:

Year:  2017        PMID: 28551734     DOI: 10.1007/s40272-017-0239-z

Source DB:  PubMed          Journal:  Paediatr Drugs        ISSN: 1174-5878            Impact factor:   3.022


  68 in total

1.  Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis.

Authors:  Mary G Boy; Cunshan Wang; Bethanie E Wilkinson; Vincent Fung-Sing Chow; Alan T Clucas; James G Krueger; Anderson S Gaweco; Samuel H Zwillich; Paul S Changelian; Gary Chan
Journal:  J Invest Dermatol       Date:  2009-02-19       Impact factor: 8.551

2.  Experience with oral tofacitinib in 8 adolescent patients with alopecia universalis.

Authors:  Leslie Castelo-Soccio
Journal:  J Am Acad Dermatol       Date:  2017-04       Impact factor: 11.527

3.  Long-term results of topical immunotherapy in children with alopecia totalis or alopecia universalis.

Authors:  A Tosti; M S Guidetti; F Bardazzi; C Misciali
Journal:  J Am Acad Dermatol       Date:  1996-08       Impact factor: 11.527

Review 4.  The role of hair follicle immune privilege collapse in alopecia areata: status and perspectives.

Authors:  Ralf Paus; Marta Bertolini
Journal:  J Investig Dermatol Symp Proc       Date:  2013-12

5.  Double-blind, placebo-controlled evaluation of topical minoxidil in extensive alopecia areata.

Authors:  V H Price
Journal:  J Am Acad Dermatol       Date:  1987-03       Impact factor: 11.527

6.  308-nm excimer laser for the treatment of alopecia areata in children.

Authors:  Nawaf Al-Mutairi
Journal:  Pediatr Dermatol       Date:  2009 Sep-Oct       Impact factor: 1.588

7.  Systemic steroids with or without 2% topical minoxidil in the treatment of alopecia areata.

Authors:  E A Olsen; S C Carson; E A Turney
Journal:  Arch Dermatol       Date:  1992-11

8.  Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.

Authors:  Regina C Betz; Lynn Petukhova; Stephan Ripke; Hailiang Huang; Androniki Menelaou; Silke Redler; Tim Becker; Stefanie Heilmann; Tarek Yamany; Madeliene Duvic; Maria Hordinsky; David Norris; Vera H Price; Julian Mackay-Wiggan; Annemieke de Jong; Gina M DeStefano; Susanne Moebus; Markus Böhm; Ulrike Blume-Peytavi; Hans Wolff; Gerhard Lutz; Roland Kruse; Li Bian; Christopher I Amos; Annette Lee; Peter K Gregersen; Bettina Blaumeiser; David Altshuler; Raphael Clynes; Paul I W de Bakker; Markus M Nöthen; Mark J Daly; Angela M Christiano
Journal:  Nat Commun       Date:  2015-01-22       Impact factor: 14.919

9.  Efficacy and safety of methotrexate in alopecia areata.

Authors:  Mariana Hammerschmidt; Fabiane Mulinari Brenner
Journal:  An Bras Dermatol       Date:  2014 Sep-Oct       Impact factor: 1.896

10.  Minoxidil induced hypertrichosis in a 2 year-old child.

Authors:  Ingrid Herskovitz; Joshua Freedman; Antonella Tosti
Journal:  F1000Res       Date:  2013-10-28
View more
  4 in total

1.  A Retrospective Study on Alopecia Areata in Children: Clinical Characteristics and Treatment Choices.

Authors:  Christina Stefanaki; George Kontochristopoulos; Eleni Hatzidimitraki; Aravella Stergiopoulou; Alexandra Katsarou; Vasiliki Vosynioti; Eleni Remountaki; Dimitrios Rigopoulos
Journal:  Skin Appendage Disord       Date:  2021-09-14

2.  Efficacy and Tolerability of Methotrexate in the Treatment of Severe Paediatric Alopecia Areata.

Authors:  Henrietta Albela; Sabeera Begum; Ai Leen Wee; Nirmala Ponnuthurai; Kin Fon Leong
Journal:  Skin Appendage Disord       Date:  2022-01-10

3.  Consensus on the treatment of alopecia areata - Brazilian Society of Dermatology.

Authors:  Paulo Müller Ramos; Alessandra Anzai; Bruna Duque-Estrada; Daniel Fernandes Melo; Flavia Sternberg; Leopoldo Duailibe Nogueira Santos; Lorena Dourado Alves; Fabiane Mulinari-Brenner
Journal:  An Bras Dermatol       Date:  2020-10-08       Impact factor: 1.896

4.  Plum-blossom needle plus Chinese herbal medicine for alopecia areata: A protocol for systematic review and meta analysis.

Authors:  Genhua Tang; Jun Xiong; Qian Fan; Han Guo; Xingchen Zhou; Siyuan Zhu; Zhiying Zhong; Jun Chen; Lunbin Lu
Journal:  Medicine (Baltimore)       Date:  2020-10-09       Impact factor: 1.817

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.