Literature DB >> 34901176

A Retrospective Study on Alopecia Areata in Children: Clinical Characteristics and Treatment Choices.

Christina Stefanaki1, George Kontochristopoulos1, Eleni Hatzidimitraki2, Aravella Stergiopoulou2, Alexandra Katsarou1, Vasiliki Vosynioti1, Eleni Remountaki1, Dimitrios Rigopoulos2.   

Abstract

BACKGROUND: Although children are affected frequently with alopecia areata (AA), data are limited on clinical characteristics and treatment choices.
MATERIALS AND METHODS: We retrospectively reviewed the records of the pediatric dermatology department over a 12-year period to identify children with AA. Clinical data were collected.
RESULTS: Three hundred and sixty-four children with AA were identified, aged 1-12 years, 214 males and 150 females. The mean age of onset was 6.6 years (±3.3). The disease presented with patches on the scalp in the majority (90.7%), whereas only 6 children had alopecia totalis or universalis. The most commonly prescribed treatment was topical steroids (69.1%), followed by the combination of topical steroids and minoxidil 2% (14.3%). Oral steroids were prescribed in only 16 children. Follow-up at 3 months was available for only 70 children and the majority (84.3%) had some hair regrowth. Hair regrowth was unrelated to the number of plaques (p = 0.257), disease location (p = 0.302), and atopy (p = 0.999). Hair regrowth only correlated with the type of treatment (p = 0.003) with potent topical and intralesional steroids giving the best results.
CONCLUSION: AA usually presents with a mild form in children, and potent topical steroids are the mainstay of treatment.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Alopecia areata; Males; Minoxidil; Ophiasis; Topical steroids

Year:  2021        PMID: 34901176      PMCID: PMC8613625          DOI: 10.1159/000518042

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  33 in total

1.  Topical use of minoxidil in children and systemic side effects.

Authors:  S Georgala; A Befon; E Maniatopoulou; C Georgala
Journal:  Dermatology       Date:  2007       Impact factor: 5.366

2.  Bilateral Half-Head Comparison of 1% Anthralin Ointment in Children with Alopecia Areata.

Authors:  Mustafa Özdemir; Ali Balevi
Journal:  Pediatr Dermatol       Date:  2017-01-03       Impact factor: 1.588

3.  Treatment of alopecia areata: An Australian expert consensus statement.

Authors:  William C Cranwell; Vivien Wy Lai; Louise Photiou; Nekma Meah; Dmitri Wall; Deepani Rathnayake; Shobha Joseph; Vijaya Chitreddy; Shyamalar Gunatheesan; Kamaldeep Sindhu; Pooja Sharma; Jack Green; Samantha Eisman; Leona Yip; Leslie Jones; Rodney Sinclair
Journal:  Australas J Dermatol       Date:  2018-11-08       Impact factor: 2.875

4.  A clinical study of childhood alopecia areata in Chandigarh, India.

Authors:  V K Sharma; B Kumar; G Dawn
Journal:  Pediatr Dermatol       Date:  1996 Sep-Oct       Impact factor: 1.588

5.  Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis.

Authors:  Abdullah Alkhalifah; Adel Alsantali; Eddy Wang; Kevin J McElwee; Jerry Shapiro
Journal:  J Am Acad Dermatol       Date:  2010-02       Impact factor: 11.527

6.  Alopecia areata: a long term follow-up study of 191 patients.

Authors:  Antonella Tosti; Sara Bellavista; Matilde Iorizzo
Journal:  J Am Acad Dermatol       Date:  2006-06-27       Impact factor: 11.527

Review 7.  Therapeutic management in paediatric alopecia areata: A systematic review.

Authors:  A Waśkiel-Burnat; M Kołodziejak; M Sikora; A Stochmal; A Rakowska; M Olszewska; L Rudnicka
Journal:  J Eur Acad Dermatol Venereol       Date:  2021-06       Impact factor: 6.166

8.  A prospective survey of pediatric dermatology clinic patients in Kuwait: an analysis of 10,000 cases.

Authors:  A Nanda; F Al-Hasawi; Q A Alsaleh
Journal:  Pediatr Dermatol       Date:  1999 Jan-Feb       Impact factor: 1.588

9.  Treatment of severe alopecia areata with intralesional steroid injections.

Authors:  Kyung Hee Chang; Salinee Rojhirunsakool; Lynne J Goldberg
Journal:  J Drugs Dermatol       Date:  2009-10       Impact factor: 2.114

10.  Clobetasol propionate, 0.05%, vs hydrocortisone, 1%, for alopecia areata in children: a randomized clinical trial.

Authors:  Patsy Lenane; Colin Macarthur; Patricia C Parkin; Bernice Krafchik; Julie DeGroot; Amina Khambalia; Elena Pope
Journal:  JAMA Dermatol       Date:  2014-01       Impact factor: 10.282

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.