Literature DB >> 28551717

Total IgM and Anti-Phosphatidylcholine IgM Antibody Secretion Continue After Clearance of Mycobacterium bovis Bacillus Calmette-Guerin Pleural Infection.

Ciara Ordoñez1,2, Musharaf Tarajia1,2, René Rivera3, Dilcia Sambrano1, Victoria Batista1, Mónica Chávez4, Denis Tapia4, Patricia L Fernández3, Amador Goodridge5.   

Abstract

The cellular immune response to Mycobacterium tuberculosis infection has been well characterized, while the humoral antibody response remains underexplored. We aimed to examine the total and anti-phospholipid IgM levels in the pleural lavage from mice with Mycobacterium bovis BCG extrapulmonary infection. We found that the levels of total and anti-phosphatidylcholine IgM antibodies remained significantly higher in infected mice as compared to non-infected mice up to day 90 after BCG infection, while the anti-cardiolipin IgM antibody levels decreased with bacteria clearance. Our findings suggest that IgM antibodies are secreted and their composition vary during early and late immune response to BCG pleurisy.

Entities:  

Keywords:  Anti-phospholipid IgM; Biomarkers; Extrapulmonary tuberculosis; Total IgM antibody

Mesh：

Substances：

Year:  2017        PMID： 28551717     DOI： 10.1007/s00408-017-0019-0

Source DB:  PubMed          Journal:  Lung        ISSN： 0341-2040            Impact factor:   2.584


  26 in total

1.  Activated B cells in the granulomas of nonhuman primates infected with Mycobacterium tuberculosis.

Authors:  Jia Yao Phuah; Joshua T Mattila; Philana L Lin; JoAnne L Flynn
Journal:  Am J Pathol       Date:  2012-06-19       Impact factor: 4.307

Review 2.  Novel strategies to identify biomarkers in tuberculosis.

Authors:  Marc Jacobsen; Jens Mattow; Dirk Repsilber; Stefan H E Kaufmann
Journal:  Biol Chem       Date:  2008-05       Impact factor: 3.915

3.  Immunohistochemical localization of immunoglobulins in bovine granulomatous lesions.

Authors:  E Momotani; M Kubo; Y Ishikawa; T Yoshino
Journal:  J Comp Pathol       Date:  1989-02       Impact factor: 1.311

4.  Development of therapeutic and prophylactic vaccine against Tuberculosis using monkey and transgenic mice models.

Authors:  Yoko Kita; Masaji Okada; Toshihiro Nakajima; Noriko Kanamaru; Satomi Hashimoto; Tetsuji Nagasawa; Yasufumi Kaneda; Shigeto Yoshida; Yasuko Nishida; Hitoshi Nakatani; Kyoko Takao; Chie Kishigami; Shiho Nishimatsu; Yuki Sekine; Yasushi Takamori; David N McMurray; E C De la Cruz; E V Tan; R M Abalos; J A Burgos; Paul Saunderson; Mitsunori Sakatani
Journal:  Hum Vaccin       Date:  2011-01-01

5.  Different cytokine patterns correlate with the extension of disease in pulmonary tuberculosis.

Authors:  A Somoskövi; G Zissel; P F Zipfel; M W Ziegenhagen; J Klaucke; H Haas; M Schlaak; J Müller-Quernheim
Journal:  Eur Cytokine Netw       Date:  1999-06       Impact factor: 2.737

Review 6.  Macrophages and control of granulomatous inflammation in tuberculosis.

Authors:  J L Flynn; J Chan; P L Lin
Journal:  Mucosal Immunol       Date:  2011-03-23       Impact factor: 7.313

Review 7.  Tuberculosis biomarkers discovery: developments, needs, and challenges.

Authors:  Robert S Wallis; Peter Kim; Stewart Cole; Debra Hanna; Bruno B Andrade; Markus Maeurer; Marco Schito; Alimuddin Zumla
Journal:  Lancet Infect Dis       Date:  2013-03-24       Impact factor: 25.071

8.  Cytokine production at the site of disease in human tuberculosis.

Authors:  P F Barnes; S Lu; J S Abrams; E Wang; M Yamamura; R L Modlin
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

9.  Novel prophylactic and therapeutic vaccine against tuberculosis.

Authors:  Masaji Okada; Yoko Kita; Toshihiro Nakajima; Noriko Kanamaru; Satomi Hashimoto; Tetsuji Nagasawa; Yasufumi Kaneda; Shigeto Yoshida; Yasuko Nishida; Hitoshi Nakatani; Kyoko Takao; Chie Kishigami; Yoshikazu Inoue; Makoto Matsumoto; David N McMurray; E C Dela Cruz; E V Tan; R M Abalos; J A Burgos; Paul Saunderson; Mitsunori Sakatani
Journal:  Vaccine       Date:  2009-02-05       Impact factor: 3.641

10.  Antiphospholipid IgM antibody response in acute and chronic Mycobacterium tuberculosis mouse infection model.

Authors:  Amador Goodridge; Tianyi Zhang; Toshiko Miyata; Sangwei Lu; Lee W Riley
Journal:  Clin Respir J       Date:  2013-10-01       Impact factor: 2.570
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  2 in total

1.  Both B-1a and B-1b cells exposed to Mycobacterium tuberculosis lipids differentiate into IgM antibody-secreting cells.

Authors:  Ciara Ordoñez; Hannah P Savage; Musharaf Tarajia; René Rivera; Cheyenne Weeks-Galindo; Dilcia Sambrano; Lee Riley; Patricia L Fernandez; Nicole Baumgarth; Amador Goodridge
Journal:  Immunology       Date:  2018-02-18       Impact factor: 7.397

2.  Do B-1 cells play a role in response to Mycobacterium tuberculosis Beijing lineages?

Authors:  Fermín Acosta; Patricia L Fernández; Amador Goodridge
Journal:  Virulence       Date:  2021-11-09       Impact factor: 5.882
  2 in total

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