Tomoki Nakamura1, Hirohisa Katagiri2, Yoji Shido3, Shunsuke Hamada4, Kenji Yamada5, Akihito Nagano6, Satoshi Yamada7, Satoshi Tsukushi8, Daisuke Ishimura9, Akihiko Matsumine10, Akihiro Sudo10, Yoshihiro Nishida4. 1. Department of Orthopaedic Surgery, Mie Graduate School of Medicine, Tsu, Japan tomoki66@clin.medic.mie-u.ac.jp. 2. Division of Orthopaedic Oncology, Sizuoka Cancer Hospital, Nagaizumi, Japan. 3. Departmemt of Orthopaedic Surgery, Hamamatsu Medical University, Hamamatsu, Japan. 4. Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan. 5. Department of Orthopedic Surgery, Aichi Cancer Center, Aichi Hospital, Okazaki, Japan. 6. Department of Orthopedic Surgery, Gifu University Graduate School of Medicine, Gifu, Japan. 7. Department of Orthopedic Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan. 8. Department of Orthopaedic Surgery, Aichi Cancer Center, Nagoya, Japan. 9. Department of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake, Japan. 10. Department of Orthopaedic Surgery, Mie Graduate School of Medicine, Tsu, Japan.
Abstract
BACKGROUND/AIM: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. PATIENTS AND METHODS: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. RESULTS: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). CONCLUSION: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis. Copyright
BACKGROUND/AIM: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. PATIENTS AND METHODS: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. RESULTS: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). CONCLUSION: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis. Copyright
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