Paola M Cannaò1,2, Giuseppe Muscogiuri1,3, U Joseph Schoepf1,4, Carlo N De Cecco1, Pal Suranyi1,4, Virginia W Lesslie1, Davide Piccini5,6, Shivraman Giri7, Akos Varga-Szemes1. 1. Department of Radiology and Radiological Science, Division of Cardiovascular Imaging. 2. Unit of Radiology, IRCCS Policlinico San Donato, San Donato Milanese. 3. Department of Imaging, Bambino Gesu Children's Hospital IRCCS, Rome, Italy. 4. Department of Medicine, Division of Cardiology, Medical University of South Carolina, Charleston, SC. 5. Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL). 6. Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland. 7. Siemens Healthineers, Chicago, IL.
Abstract
PURPOSE: The aim of this study was to prospectively evaluate the technical feasibility of a noncontrast magnetic resonance angiography (MRA) protocol using investigational prototype self-navigated 3D (SN3D) radial whole-heart and quiescent-interval single-shot (QISS) pulse sequences regarding their potential in planning transcatheter aortic valve replacement (TAVR). MATERIALS AND METHODS: Five patients (76±7 y) with severe aortic valve stenosis and prior computed tomographic angiography (CTA) for TAVR planning and 10 healthy volunteers (28±6 y) underwent noncontrast MRA on a 1.5 T system. A SN3D whole-heart acquisition was used to assess the aortic root anatomy. Evaluation of the aortoiliac access route was performed with both SN3D and QISS. Measurements were compared among SN3D, QISS, and CTA using a paired t test or 1-way analysis of variance. Image quality ratings and contrast-to-noise ratios (CNR) were analyzed using Mann-Whitney U tests. Interobserver agreement was evaluated using Cohen's κ. RESULTS: The combined SN3D and QISS protocol provided a 10.1±1.6-minute acquisition time. TAVR-relevant evaluation was technically feasible in healthy volunteers. All measurements showed good agreement with CTA in patients (all P>0.098). SN3D and QISS produced similar image quality both in volunteers and in patients (all P>0.122). There was no difference in qualitative ratings between MRA and CTA (all P>0.119). Interobserver agreement was good for MRA (κ=0.71 to 0.76) and excellent for CTA (κ=0.82 to 0.84). Thoracic SN3D provided a similar CNR compared with CTA (P=0.117). CTA yielded higher CNR in the abdominopelvic region compared with QISS (P=0.006). CONCLUSIONS: A noncontrast MRA protocol combining SN3D and QISS acquisitions for the assessment of cardiac and vascular access route anatomy has technical feasibility for TAVR planning.
PURPOSE: The aim of this study was to prospectively evaluate the technical feasibility of a noncontrast magnetic resonance angiography (MRA) protocol using investigational prototype self-navigated 3D (SN3D) radial whole-heart and quiescent-interval single-shot (QISS) pulse sequences regarding their potential in planning transcatheter aortic valve replacement (TAVR). MATERIALS AND METHODS: Five patients (76±7 y) with severe aortic valve stenosis and prior computed tomographic angiography (CTA) for TAVR planning and 10 healthy volunteers (28±6 y) underwent noncontrast MRA on a 1.5 T system. A SN3D whole-heart acquisition was used to assess the aortic root anatomy. Evaluation of the aortoiliac access route was performed with both SN3D and QISS. Measurements were compared among SN3D, QISS, and CTA using a paired t test or 1-way analysis of variance. Image quality ratings and contrast-to-noise ratios (CNR) were analyzed using Mann-Whitney U tests. Interobserver agreement was evaluated using Cohen's κ. RESULTS: The combined SN3D and QISS protocol provided a 10.1±1.6-minute acquisition time. TAVR-relevant evaluation was technically feasible in healthy volunteers. All measurements showed good agreement with CTA in patients (all P>0.098). SN3D and QISS produced similar image quality both in volunteers and in patients (all P>0.122). There was no difference in qualitative ratings between MRA and CTA (all P>0.119). Interobserver agreement was good for MRA (κ=0.71 to 0.76) and excellent for CTA (κ=0.82 to 0.84). Thoracic SN3D provided a similar CNR compared with CTA (P=0.117). CTA yielded higher CNR in the abdominopelvic region compared with QISS (P=0.006). CONCLUSIONS: A noncontrast MRA protocol combining SN3D and QISS acquisitions for the assessment of cardiac and vascular access route anatomy has technical feasibility for TAVR planning.
Authors: Federico E Mordini; Conor F Hynes; Richard L Amdur; Jeffrey Panting; Dominic A Emerson; Jason Morrissette; Erin Goheen-Thomas; Michael D Greenberg; Gregory D Trachiotis Journal: Int J Cardiovasc Imaging Date: 2021-03-10 Impact factor: 2.357
Authors: Mathias Pamminger; Gert Klug; Christof Kranewitter; Martin Reindl; Sebastian J Reinstadler; Benjamin Henninger; Christina Tiller; Magdalena Holzknecht; Christian Kremser; Axel Bauer; Werner Jaschke; Bernhard Metzler; Agnes Mayr Journal: Eur Radiol Date: 2020-04-22 Impact factor: 5.315
Authors: Basel Yacoub; Robert E Stroud; Davide Piccini; U Joseph Schoepf; John Heerfordt; Jérôme Yerly; Lorenzo Di Sopra; Jonathan D Rollins; D Alan Turner; Tilman Emrich; Fei Xiong; Pal Suranyi; Akos Varga-Szemes Journal: J Cardiovasc Magn Reson Date: 2021-02-08 Impact factor: 5.364