Literature DB >> 28540477

[Personalization in the medicine of the future : Opportunities and risks].

N P Malek1.   

Abstract

Personalized medicine is not a new concept. The renaissance of the term is due to the enormous progress in gene sequencing technology and functional imaging, as well as the development of targeted therapies. Application of these technologies in clinical medicine will necessitate infrastructural as well as organizational and educational changes in the healthcare system. An important change required already in the short-term is the introduction of centralized structures, preferably in university clinics, which adopt these innovations and incorporate them into clinical care. Simultaneously, the collation and use of large quantities of relevant data from highly variable sources must be successfully mastered, in order to pave the way for disruptive technologies such as artificial intelligence.

Keywords:  Databases as topic; Education, professional; Networking, regional; Personalized medicine; Privatization of data

Mesh:

Year:  2017        PMID: 28540477     DOI: 10.1007/s00108-017-0265-5

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  5 in total

1.  Clinical application of pharmacogenetics.

Authors:  B B Spear; M Heath-Chiozzi; J Huff
Journal:  Trends Mol Med       Date:  2001-05       Impact factor: 11.951

Review 2.  Mathematical modeling in cancer drug discovery.

Authors:  Zhihui Wang; Thomas S Deisboeck
Journal:  Drug Discov Today       Date:  2013-07-04       Impact factor: 7.851

3.  Precision medicine--personalized, problematic, and promising.

Authors:  J Larry Jameson; Dan L Longo
Journal:  N Engl J Med       Date:  2015-05-27       Impact factor: 91.245

4.  Stop the privatization of health data.

Authors:  John T Wilbanks; Eric J Topol
Journal:  Nature       Date:  2016-07-21       Impact factor: 49.962

Review 5.  Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials.

Authors:  Maria Schwaederle; Melissa Zhao; J Jack Lee; Alexander M Eggermont; Richard L Schilsky; John Mendelsohn; Vladimir Lazar; Razelle Kurzrock
Journal:  J Clin Oncol       Date:  2015-08-24       Impact factor: 44.544

  5 in total

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