Literature DB >> 28537655

Comparative effectiveness and impact on health-related quality of life of hysterectomy vs. levonorgestrel intra-uterine system for abnormal uterine bleeding.

G Cozza1, A Pinto, V Giovanale, P Bianchi, A Guarino, R Marziani, A Frega, D Caserta.   

Abstract

OBJECTIVE: To compare hysterectomy and levonorgestrel intra-uterine system (LNG-IUS) for the treatment of abnormal uterine bleeding (AUB) and iron deficiency anemia. PATIENTS AND METHODS: Retrospective study evaluating quality of life, sexual function, satisfaction and blood hemoglobin concentration improvement in 60 pre-menopausal women treated with hysterectomy or LNG-IUS. All analysis was performed with statistical software SPSS 21.0 (SPSS Inc., Chicago, IL, USA).
RESULTS: Despite superior control of bleeding and dysmenorrhea observed after hysterectomy, LNG-IUS showed similar impact on blood hemoglobin levels, quality of life, satisfaction and sexual function resulting more cost-effective.
CONCLUSIONS: In the absence of contraindications, LNG-IUS should always be the first therapeutic choice for chronic AUB. Surgical treatment must be considered as an "extrema ratio".

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Year:  2017        PMID: 28537655

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  4 in total

1.  The cost of diagnosing endometrial cancer: Quantifying the healthcare cost of an abnormal uterine bleeding workup.

Authors:  Simrit K Warring; Bijan Borah; James Moriarty; Rachel Gullerud; Maureen A Lemens; Christopher Destephano; Mark E Sherman; Jamie N Bakkum-Gamez
Journal:  Gynecol Oncol       Date:  2021-10-28       Impact factor: 5.482

2.  Oral and intrauterine progestogens for atypical endometrial hyperplasia.

Authors:  Li Luo; Bing Luo; Ying Zheng; Heng Zhang; Jing Li; Neil Sidell
Journal:  Cochrane Database Syst Rev       Date:  2018-12-04

3.  Analysis of the effect of laparoscopy and hysteroscopy on ovarian function, immune function and quality of sexual life of patients with hysteromyoma at different ages.

Authors:  Yuxue Zhang; Xiaoli Gu; Yuejin Meng; Haizhou Guo; Jiehua Du; Wei Xing
Journal:  Oncol Lett       Date:  2017-12-15       Impact factor: 2.967

4.  High prevalence of abnormal menstruation among women living with HIV in Canada.

Authors:  Christina Valiaveettil; Mona Loutfy; V Logan Kennedy; Sheila Caddy; Mark Yudin; Tracey Conway; Erin Ding; Paul Sereda; Alexandra de Pokomandy; Angela Kaida
Journal:  PLoS One       Date:  2019-12-27       Impact factor: 3.240

  4 in total

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