Literature DB >> 28537279

Synthesis of biotin-labelled core glycans of GPI anchors and their application in the study of GPI interaction with pore-forming bacterial toxins.

Jian Gao1, Zhifang Zhou, Jiatong Guo, Zhongwu Guo.   

Abstract

A convergent strategy was developed for the first-time synthesis of biotin-labeled GPI core glycans. These GPI conjugates are useful for various biological studies showcased by their application in the scrutiny of pore-forming bacterial toxin-GPI interaction, revealing that the phosphate group at the GPI inositol 1-O-position had a significant impact on GPI-toxin binding.

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Year:  2017        PMID： 28537279      PMCID： PMC5633853          DOI： 10.1039/c7cc03056h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  24 in total

1.  Iterative one-pot synthesis of oligosaccharides.

Authors:  Xuefei Huang; Lijun Huang; Haisheng Wang; Xin-Shan Ye
Journal:  Angew Chem Int Ed Engl       Date:  2004-10-04       Impact factor: 15.336

2.  Streptococcus agalactiae CAMP factor binds to GPI-anchored proteins.

Authors:  Shenhui Lang; Jie Xue; Zhongwu Guo; Michael Palmer
Journal:  Med Microbiol Immunol       Date:  2006-06-14       Impact factor: 3.402

Review 3.  Pore-forming bacterial protein hemolysins (cytolysins).

Authors:  V Braun; T Focareta
Journal:  Crit Rev Microbiol       Date:  1991       Impact factor: 7.624

Review 4.  Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures.

Authors:  M A Ferguson; A F Williams
Journal:  Annu Rev Biochem       Date:  1988       Impact factor: 23.643

Review 5.  Chemical synthesis of glycosylphosphatidylinositol anchors.

Authors:  Benjamin M Swarts; Zhongwu Guo
Journal:  Adv Carbohydr Chem Biochem       Date:  2012       Impact factor: 12.200

Review 6.  The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors.

Authors:  P T Englund
Journal:  Annu Rev Biochem       Date:  1993       Impact factor: 23.643

7.  Glycosylphosphatidylinositol anchors of membrane glycoproteins are binding determinants for the channel-forming toxin aerolysin.

Authors:  D B Diep; K L Nelson; S M Raja; E N Pleshak; J T Buckley
Journal:  J Biol Chem       Date:  1998-01-23       Impact factor: 5.157

8.  A general method for synthesis of GPI anchors illustrated by the total synthesis of the low-molecular-weight antigen from Toxoplasma gondii.

Authors:  Yu-Hsuan Tsai; Sebastian Götze; Nahid Azzouz; Heung Sik Hahm; Peter H Seeberger; Daniel Varon Silva
Journal:  Angew Chem Int Ed Engl       Date:  2011-09-05       Impact factor: 15.336

9.  Convergent synthesis of a GPI containing an acylated inositol.

Authors:  Jie Xue; Zhongwu Guo
Journal:  J Am Chem Soc       Date:  2003-12-31       Impact factor: 15.419

Review 10.  The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research.

Authors:  M A Ferguson
Journal:  J Cell Sci       Date:  1999-09       Impact factor: 5.285
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  1 in total

1.  Crystal structure of the Streptococcus agalactiae CAMP factor provides insights into its membrane-permeabilizing activity.

Authors:  Tengchuan Jin; Eric Brefo-Mensah; Weirong Fan; Weihong Zeng; Yajuan Li; Yuzhu Zhang; Michael Palmer
Journal:  J Biol Chem       Date:  2018-06-08       Impact factor: 5.157
  1 in total

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