Literature DB >> 28534220

Is decompressive surgery the only treatment option? A case series of patients with spinal tuberculosis in advanced pregnancy.

Ashok K Rathod1, Vishwajeet Singh2, Prateek Patil3, Hemant Singh1.   

Abstract

PURPOSE: To present cases of spinal tuberculosis in advanced pregnancy treated on anti-tuberculous drug regimen with successful outcome and proposing alternative paradigm to surgical decompression. A case series of five patients in stages of advanced pregnancy with neurologic deterioration and spinal tuberculosis were reported and treated.
METHODS: Five patients with backache in advanced stages of pregnancy were reported. Patients were diagnosed as cases of spinal tuberculosis on further imaging studies. Patients were treated and followed up till complete clinical and radiological recovery.
RESULTS: Four out of five patients were treated conservatively on ATT and rest. One patient underwent decompression without instrumentation. All patients recovered neurologically. There were foetal complications in two cases with foetal demise. One patient who underwent surgical decompression had preterm labour with still birth, apparently due to adverse reactions with anaesthetic drugs.
CONCLUSION: Spinal tuberculosis in pregnancy is a rare occurrence. Hesitation in performing radiographs complicates the outcome with delay in diagnosis and neurological compromise. There are no clear guidelines for treatment of such cases. Conservative treatment with ATT in pregnant patients may be a viable approach. Neurological compromise does not mandate surgical decompression, which in itself is not devoid of complications. Concern of foetal complications is high in surgical treatment.

Entities:  

Keywords:  Advanced pregnancy; Anti-tubercular therapy; Conservative treatment; Spinal tuberculosis

Mesh:

Year:  2017        PMID: 28534220     DOI: 10.1007/s00586-017-5143-2

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  26 in total

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Authors:  Roisin Ní Mhuireachtaigh; David A O'Gorman
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4.  API TB Consensus Guidelines 2006: Management of pulmonary tuberculosis, extra-pulmonary tuberculosis and tuberculosis in special situations.

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Journal:  J Assoc Physicians India       Date:  2006-03

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Journal:  J Bone Joint Surg Am       Date:  1999-09       Impact factor: 5.284

6.  Late onset of progressive neurological deficits in severe angular kyphosis related to tuberculosis spondylitis.

Authors:  Kee-Yong Ha; Young-Hoon Kim
Journal:  Eur Spine J       Date:  2015-05-19       Impact factor: 3.134

7.  Obstetrical outcomes among women with extrapulmonary tuberculosis.

Authors:  N Jana; K Vasishta; S C Saha; K Ghosh
Journal:  N Engl J Med       Date:  1999-08-26       Impact factor: 91.245

8.  Single-stage anterior autogenous bone grafting and instrumentation in the surgical management of spinal tuberculosis.

Authors:  Li-Yang Dai; Lei-Sheng Jiang; Wei Wang; Yi-Min Cui
Journal:  Spine (Phila Pa 1976)       Date:  2005-10-15       Impact factor: 3.468

9.  Non-obstetric surgery during gestation: risk factors for lower birthweight.

Authors:  Thomas M Jenkins; Suzanne F Mackey; Elisa M Benzoni; Jorge E Tolosa; Anthony C Sciscione
Journal:  Aust N Z J Obstet Gynaecol       Date:  2003-02       Impact factor: 2.100

10.  Simultaneous anterior decompression and posterior instrumentation of the tuberculous spine using an anterolateral extrapleural approach.

Authors:  A K Jain; I K Dhammi; B Prashad; S Sinha; P Mishra
Journal:  J Bone Joint Surg Br       Date:  2008-11
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  3 in total

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2.  Examining family planning and adverse pregnancy outcomes for women with active tuberculosis disease: a systematic review.

Authors:  Yen Nguyen; Katherine C McNabb; Jason E Farley; Nicole Warren
Journal:  BMJ Open       Date:  2022-03-28       Impact factor: 3.006

3.  Comparison of Affected-Vertebra Fixation of Cortical Bone Trajectory Screw and Pedicle Screw for Lumbar Tuberculosis: A Minimum 3-Year Follow-Up.

Authors:  Peng Zhang; Jiekai Ye; Lixia Huang; Xiaozhang Ying; Bo Zhu; Yanghui Jin; Jun Fei; Shiyuan Shi; Qi Zheng
Journal:  Biomed Res Int       Date:  2022-07-21       Impact factor: 3.246

  3 in total

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