| Literature DB >> 28533245 |
Dandan Yin1, Dong Dong2,3, Ke Li4, Lei Zhang1, Jianliang Liang1, Yang Yang2, Nana Wu1, Yiyan Bao1, Chuanqing Wang5, Fupin Hu6,3.
Abstract
Five OXA-232 carbapenemase-producing Klebsiella pneumoniae isolates, belonging to the pandemic clone sequence type 15 (ST15), were isolated from neonates and coproduced blaCTX-M-15 and blaSHV-1 genes. All isolates were resistant to ertapenem (MICs of >32 μg/ml) and meropenem (MICs of 4 to 8 μg/ml) and susceptible or intermediate to imipenem (MICs of 1 to 2 μg/ml). The blaOXA-232 gene was located on a ColE-type transformable plasmid of 6,141 bp. To the best of our knowledge, this is the first report of OXA-232 carbapenemase among clinical isolates in China.Entities:
Keywords: Klebsiella pneumoniae; OXA-232; ST15; clonal dissemination; neonates
Mesh:
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Year: 2017 PMID: 28533245 PMCID: PMC5527636 DOI: 10.1128/AAC.00385-17
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191