Zarrin Banikazemi1, Naghmeh Mokhber2, Mohammad Safarian1, Mohsen Mazidi1, Hamed Mirzaei3, Habibollah Esmaily4, Mahmoud Reza Azarpazhooh5, Fatemeh Ghafouri-Taleghani1, Majid Ghayour-Mobarhan6, Gordon A Ferns7. 1. Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran. 2. Departemant of Psychiatrics, Faculty of Medicine, Psychiatric Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. 3. Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. 4. Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran; Department of Statistics, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran. 5. Cardiovascular Research Center, Faculty of Medicine, MUMS, Azadi Square, Pardise Daneshgah, Mashhad, Iran. 6. Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran; Cardiovascular Research Center, Faculty of Medicine, MUMS, Azadi Square, Pardise Daneshgah, Mashhad, Iran. Electronic address: ghayourm@mums.ac.ir. 7. Division of Medical Education, Brighton & Sussex Medical School, Rm 342, Mayfield House, University of Brighton, BN1 9PH, United Kingdom.
Abstract
OBJECTIVE: There is a high prevalence of depressive disorders in all regions of the world. The importance of dietary factors in the causation of depression is suggested from epidemiologic studies in Western countries, but evidence from non-Western populations are lacking. We aimed to assess the relationship between dietary factors with depression scores in a cohort from north eastern Iran. METHODS: A total of 7172 subjects (2725 men and 4447 women) were recruited. Dietary intake was assessed using a 24-h dietary recall questionnaire, and depressive symptoms were assessed using the Beck's depression questionnaire. RESULTS: The age of the population samples were 49.3 ± 8.2 years for the male and 48.1 ± 8.0 years for the female subgroups. Crude intake of MUFA, SFA and TFA in patients was associated with depression scores. On the other hand, there were significant correlations between depression score and total energy adjusted intake of trans-fatty acid (TFA), cholesterol, vitamin E (p < 0.01 for all parameters). CONCLUSION: There was an association between diet and depression score among a representative sample of individuals from north eastern Iran, with MUFA intake being inversely related, and vitamin E intake being directly related to Beck's depression score. However it cannot be determined whether this is related to the causation of depression in this cross sectional study.
OBJECTIVE: There is a high prevalence of depressive disorders in all regions of the world. The importance of dietary factors in the causation of depression is suggested from epidemiologic studies in Western countries, but evidence from non-Western populations are lacking. We aimed to assess the relationship between dietary factors with depression scores in a cohort from north eastern Iran. METHODS: A total of 7172 subjects (2725 men and 4447 women) were recruited. Dietary intake was assessed using a 24-h dietary recall questionnaire, and depressive symptoms were assessed using the Beck's depression questionnaire. RESULTS: The age of the population samples were 49.3 ± 8.2 years for the male and 48.1 ± 8.0 years for the female subgroups. Crude intake of MUFA, SFA and TFA in patients was associated with depression scores. On the other hand, there were significant correlations between depression score and total energy adjusted intake of trans-fatty acid (TFA), cholesterol, vitamin E (p < 0.01 for all parameters). CONCLUSION: There was an association between diet and depression score among a representative sample of individuals from north eastern Iran, with MUFA intake being inversely related, and vitamin E intake being directly related to Beck's depression score. However it cannot be determined whether this is related to the causation of depression in this cross sectional study.
Authors: Arpita Das; Robert G Cumming; Vasi Naganathan; Rosilene V Ribeiro; David G Le Couteur; David J Handelsman; Louise M Waite; Vasant Hirani Journal: Eur J Nutr Date: 2020-05-08 Impact factor: 5.614