| Literature DB >> 28528688 |
Mallory E Harden1, Karl Munger2.
Abstract
Human papillomaviruses are small DNA viruses with a tropism for squamous epithelia. A unique aspect of human papillomavirus molecular biology involves dependence on the differentiation status of the host epithelial cell to complete the viral lifecycle. A small group of these viruses are the etiologic agents of several types of human cancers, including oral and anogenital tract carcinomas. This review focuses on the basic molecular biology of human papillomaviruses.Entities:
Keywords: Cervical cancer; Epithelial differentiation; Human papillomavirus; Oncogene; Tumor suppressor; Vaccine
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Year: 2016 PMID: 28528688 PMCID: PMC5500221 DOI: 10.1016/j.mrrev.2016.07.002
Source DB: PubMed Journal: Mutat Res Rev Mutat Res ISSN: 1383-5742 Impact factor: 5.657