| Literature DB >> 28526660 |
Pallabita Chowdhury1, Allison M Roberts1, Sheema Khan1, Bilal B Hafeez1, Subhash C Chauhan1, Meena Jaggi1, Murali M Yallapu2.
Abstract
Magnetic nanoparticles (MNPs) play a vital role for improved imaging applications. Recently, a number of studies demonstrate MNPs can be applied for targeted delivery, sustained release of therapeutics, and hyperthermia. Based on stable particle size and shape, biocompatibility, and inherent contrast enhancement characteristics, MNPs have been encouraged for pre-clinical studies and human use. As a theranostic platform development, MNPs need to balance both delivery and imaging aspects. Thus, this review provides significant insight and advances in the theranostic role of MNPs through the documentation of unique magnetic nanoparticles used in prostate cancer, their interaction with prostate cancer cells, in vivo fate, targeting, and biodistribution. Specific and custom-made applications of various novel nanoformulations in prostate cancer are discussed.Entities:
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Year: 2017 PMID： 28526660 PMCID： PMC5565688 DOI： 10.1016/j.drudis.2017.04.018
Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851