| Literature DB >> 28524668 |
Mario M Alvarez1, Joanna Aizenberg2, Mostafa Analoui3, Anne M Andrews, Gili Bisker, Edward S Boyden, Roger D Kamm, Jeffrey M Karp, David J Mooney2, Rahmi Oklu4, Dan Peer, Michelle Stolzoff, Michael S Strano, Grissel Trujillo-de Santiago1, Thomas J Webster5, Paul S Weiss, Ali Khademhosseini6.
Abstract
We discuss the state of the art and innovative micro- and nanoscale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applications. We take the design of point-of-care applications and the capture of circulating tumor cells as illustrative examples of the integration of micro- and nanotechnologies into solutions of diagnostic challenges. We describe several novel nanotechnologies that enable imaging cellular structures and molecular events. In therapeutics, we describe the utilization of micro- and nanotechnologies in applications including drug delivery, tissue engineering, and pharmaceutical development/testing. In addition, we discuss relevant challenges that micro- and nanotechnologies face in achieving cost-effective and widespread clinical implementation as well as forecasted applications of micro- and nanotechnologies in medicine.Entities:
Mesh：
Year: 2017 PMID： 28524668 DOI： 10.1021/acsnano.7b01493
Source DB: PubMed Journal: ACS Nano ISSN： 1936-0851 Impact factor: 15.881