| Literature DB >> 28521694 |
Arti Vashist1, Ajeet Kaushik1, Kayla Alexis1, Rahul Dev Jayant1, Vidya Sagar1, Atul Vashist2, Madhavan Nair1.
Abstract
The emergence of injectable hydrogels as biomaterials has been a revolutionary breakthrough in the field of on-demand drug delivery and tissue engineering. The promising features of these systems include their biodegradability, biocompatibility, permeability, ease of the surgical implantation, and most importantly exhibit minimally invasiveness. These hydrogels have been explored as sustained and on-demand release carriers for the various bioactive agents, growth factors, live cells, various hydrophobic drugs and as extracellular matrices for tissue engineering. Present review is an attempt to highlight the recent systems explored for on-demand drug release and tissue engineering. It also gives an overview of the role of nanotechnology in the advancements of injectable hydrogels. The future prospects and challenges of these hydrogels have also been addressed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: Injectable hydrogels; biomaterials; chitosan; drug delivery; nanomedicine; nanotechnology; pluronics
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Year: 2017 PMID： 28521694 PMCID： PMC6889087 DOI： 10.2174/1381612823666170516144914
Source DB: PubMed Journal: Curr Pharm Des ISSN： 1381-6128 Impact factor: 3.116