Literature DB >> 2852004

Abilities of peroxidases to catalyse peroxidase-oxidase oxidation of thiols.

B E Svensson1.   

Abstract

The abilities of various peroxidases to catalyse the peroxidase-oxidase oxidation of seven aminothiols were studied. Cysteamine and cysteine esters were found to be peroxidase-oxidase substrates for eosinophil peroxidase and myeloperoxidase, whereas other thiols tested were inactive or poorly active with these peroxidases. With lactoperoxidase and horseradish peroxidase, all the tested thiols were inactive or poorly active as peroxidase-oxidase substrates. These studies suggest that a main reason for thiols being poor peroxidase-oxidase substrates is because these thiols are poor peroxidatic substrates.

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Year:  1988        PMID: 2852004      PMCID: PMC1135480          DOI: 10.1042/bj2560757

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  32 in total

1.  Raman characterization of human leukocyte myeloperoxidase and bovine spleen green haemoprotein. Insight into chromophore structure and evidence that the chromophores of myeloperoxidase are equivalent.

Authors:  G T Babcock; R T Ingle; W A Oertling; J C Davis; B A Averill; C L Hulse; D J Stufkens; B G Bolscher; R Wever
Journal:  Biochim Biophys Acta       Date:  1985-03-22

2.  Thyroid peroxidase selects the mechanism of either 1- or 2-electron oxidation of phenols, depending on their substituents.

Authors:  M Nakamura; I Yamazaki; T Kotani; S Ohtaki
Journal:  J Biol Chem       Date:  1985-11-05       Impact factor: 5.157

3.  The reductive cleavage of myeloperoxidase in half, producing enzymically active hemi-myeloperoxidase.

Authors:  P C Andrews; N I Krinsky
Journal:  J Biol Chem       Date:  1981-05-10       Impact factor: 5.157

4.  Comparisons between hog intestinal peroxidase and bovine lactoperoxidase-compound I formation and inhibition by benzhydroxamic acid.

Authors:  S Kimura; I Yamazaki
Journal:  Arch Biochem Biophys       Date:  1979-12       Impact factor: 4.013

5.  Free radical metabolites of L-cysteine oxidation.

Authors:  L S Harman; C Mottley; R P Mason
Journal:  J Biol Chem       Date:  1984-05-10       Impact factor: 5.157

6.  Oxidation of indole-3-acetic acid by peroxidase: involvement of reduced peroxidase and compound III with superoxide as a product.

Authors:  A M Smith; W L Morrison; P J Milham
Journal:  Biochemistry       Date:  1982-08-31       Impact factor: 3.162

7.  Oxidation of glutathione by the myeloperoxidase system.

Authors:  R M Turkall; M F Tsan
Journal:  J Reticuloendothel Soc       Date:  1982-04

8.  Some properties of human eosinophil peroxidase, a comparison with other peroxidases.

Authors:  B G Bolscher; H Plat; R Wever
Journal:  Biochim Biophys Acta       Date:  1984-01-31

9.  Mechanism of halide-stimulated activity of chloroperoxidase evidence for enzymatic formation of free hypohalous acid.

Authors:  B W Griffin
Journal:  Biochem Biophys Res Commun       Date:  1983-11-15       Impact factor: 3.575

10.  Human eosinophil peroxidase: purification and characterization.

Authors:  M G Carlson; C G Peterson; P Venge
Journal:  J Immunol       Date:  1985-03       Impact factor: 5.422

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  4 in total

1.  Glutathione-induced radical formation on lactoperoxidase does not correlate with the enzyme's peroxidase activity.

Authors:  Marcelo G Bonini; Arno G Siraki; Suchandra Bhattacharjee; Ronald P Mason
Journal:  Free Radic Biol Med       Date:  2007-01-08       Impact factor: 7.376

2.  A comparative analysis of the influence of human salivary enzymes on odorant concentration in three palm wines.

Authors:  Ola Lasekan
Journal:  Molecules       Date:  2013-09-25       Impact factor: 4.411

3.  Oxidation of 2-hydroxynevirapine, a phenolic metabolite of the anti-HIV drug nevirapine: evidence for an unusual pyridine ring contraction.

Authors:  Alexandra M M Antunes; Muna Sidarus; David A Novais; Shrika G Harjivan; Pedro P Santos; João L Ferreira da Silva; Frederick A Beland; M Matilde Marques
Journal:  Molecules       Date:  2012-03-05       Impact factor: 4.411

4.  L-cysteine methyl ester overcomes the deleterious effects of morphine on ventilatory parameters and arterial blood-gas chemistry in unanesthetized rats.

Authors:  Paulina M Getsy; Santhosh M Baby; Walter J May; James N Bates; Christopher R Ellis; Michael G Feasel; Christopher G Wilson; Tristan H J Lewis; Benjamin Gaston; Yee-Hsee Hsieh; Stephen J Lewis
Journal:  Front Pharmacol       Date:  2022-09-28       Impact factor: 5.988

  4 in total

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