| Literature DB >> 28513734 |
Alessandro Del Grosso1, Lavrentis-Dimitrios Galanopoulos1, Cookson K C Chiu1, Guy J Clarkson1, Peter B O Connor1, Martin Wills1.
Abstract
A series of strained alkynes were prepared from 2,2'-dihydroxy-biaryls. Several were characterised by X-ray crystallography, revealing strained C(sp)-C(sp)-C(sp3) bond angles in the range of 163-167°. Their cycloadditions with azides proceed without a catalyst. Functionalised versions of these reagents have potential applications to materials synthesis and bioconjugations.Entities:
Year: 2017 PMID： 28513734 DOI： 10.1039/c7ob00991g
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876